Present Application and Perspectives of Organoid Imaging Technology.

Present Application and Perspectives of Organoid Imaging Technology.
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类器官成像技术的应用现状及展望

DOI:
10.3390/bioengineering9030121
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发表时间:
2022-03-16
期刊:
Bioengineering (Basel, Switzerland)
影响因子:
--
通讯作者:
Xiao P
Xiao P
中科院分区:
其他
文献类型:
--
作者:
Fei K;Zhang J;Yuan J;Xiao P

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An organoid is a miniaturized and simplified in vitro model with a similar structure and function to a real organ. In recent years, the use of organoids has increased explosively in the field of growth and development, disease simulation, drug screening, cell therapy, etc. In order to obtain necessary information, such as morphological structure, cell function and dynamic signals, it is necessary and important to directly monitor the culture process of organoids. Among different detection technologies, imaging technology is a simple and convenient choice and can realize direct observation and quantitative research. In this review, the principle, advantages and disadvantages of imaging technologies that have been applied in organoids research are introduced. We also offer an overview of prospective technologies for organoid imaging. This review aims to help biologists find appropriate imaging techniques for different areas of organoid research, and also contribute to the development of organoid imaging systems.
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