The binding of human milk lactoferrin to immunoglobulin A
The binding of human milk lactoferrin to immunoglobulin A
复制标题
人乳乳铁蛋白与免疫球蛋白 A 的结合
DOI：
10.1016/0014-5793(84)80246-x
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发表时间：
1984
期刊：
影响因子：
3.5
通讯作者：
W. Brown
中科院分区：
文献类型：
--
作者：
Toshiteru Watanabe;H. Nagura;Watanabe Keiichi;W. Brown
人们认识到，在人乳中，一定量的乳铁蛋白（LF）天然结合到分泌型伊加（sIgA）上。由于不仅分泌成分（SC）而且LF通过二硫键断裂从sIgA释放，可以想象LF与伊加以及SC天然结合。进行LF和伊加的体外结合试验，并通过使用IgA-Sepharose 4 B亲和柱确认结合。
It was recognized that in human milk some amounts of lactoferrin (LF) were naturally bound to secretory IgA (sIgA). Since not only secretory component (SC) but also LF was released from sIgA by disulfide bond cleavage, it is conceivable that LF is naturally bound to IgA as well as SC. An in vitro binding test to LF and IgA was performed and the binding was confirmed by the use of an IgA—Sepharose 4B affinity column.
影响因子：
6.4
作者：
S. Stephens;J. Dolby;J. Montreuil;G. Spik
通讯作者：
S. Stephens;J. Dolby;J. Montreuil;G. Spik