Preoperative Fall Risk Assessment Score as a Prognostic Factor in Esophageal Cancer Patients after Esophagectomy.
Preoperative Fall Risk Assessment Score as a Prognostic Factor in Esophageal Cancer Patients after Esophagectomy.
复制标题
DOI：
10.3390/jcm10245966
复制
发表时间：
2021-12-19
影响因子：
3.9
通讯作者：
Ueno H
中科院分区：
文献类型：
--
作者：
Kouzu K;Tsujimoto H;Ishibashi Y;Shinada H;Oikawa I;Kishi Y;Shinomiya N;Ueno H
目前的研究调查了术前跌倒风险评估评分（FRAS）对食管癌（EC）患者长期跌倒的影响。共161例接受根治性手术的EC患者根据其FRAS分为高风险（95，41.0%）和低风险（66，41.0%）组。本研究旨在探讨FRAS与临床病理结果和肿瘤之间的关系。因此，高风险组的患者年龄明显大于低风险组，Charlson合并症指数明显高于低风险组。两组病理结果无显著性差异。高风险组的总生存率（OS）和无复发生存率（RFS）显著低于低风险组（分别为p = 0.004和0.001）。多变量分析确定高FRAS是OS不良的独立预后因素，风险比为1.75（p = 0.033）。此外，排除年龄类别后对数据的重新分析显示，高风险组的OS（p = 0.004）和RFS（p = 0.003）显著低于低风险组。因此，FRAS可以被认为是一种有用的方法，用于评估脆弱性和EC的潜在预后因素。
The current study investigated the impact of preoperative fall risk assessment score (FRAS) on long-term prognoses in patients with esophageal cancer (EC). A total of 161 patients with EC who underwent curative surgery were classified into a high-risk (95, 41.0%) and low-risk (66, 41.0%) groups according to their FRAS. This study investigated the relationships between the FRAS and clinicopathological findings and prognoses. Accordingly, patients in the high-risk group were significantly older and had a significantly higher Charlson comorbidity index than those in the low-risk group. No significant difference was found in pathological findings between both groups. The high-risk group had significantly lower overall survival (OS) and relapse-free survival (RFS) rates than the low-risk group (p = 0.004 and 0.001, respectively). Multivariate analysis identified high FRAS as an independent prognostic factor for poor OS, with a hazard ratio of 1.75 (p = 0.033). Moreover, re-analysis of the data after excluding age as a category showed that the high-risk group had significantly worse OS (p = 0.004) and RFS (p = 0.003) than the low-risk group. The FRAS can, therefore, be considered a useful method for assessing frailty and a potential prognostic factor for EC.
登录
查看更多内容
食管癌实践指南2017年由日本食道协会编辑：第1部分。
DOI：
10.1007/s10388-018-0641-9
发表时间：
2019-01
期刊：
Esophagus : official journal of the Japan Esophageal Society
影响因子：
--
作者：
Kitagawa Y;Uno T;Oyama T;Kato K;Kato H;Kawakubo H;Kawamura O;Kusano M;Kuwano H;Takeuchi H;Toh Y;Doki Y;Naomoto Y;Nemoto K;Booka E;Matsubara H;Miyazaki T;Muto M;Yanagisawa A;Yoshida M
通讯作者：
Yoshida M
影响因子：
15.9
作者：
STRASSMANN, G;FONG, M;NORDAN, RP
通讯作者：
NORDAN, RP
影响因子：
3.7
作者：
Ando, Nobutoshi;Kato, Hoichi;Fukuda, Haruhiko
通讯作者：
Fukuda, Haruhiko
食管癌实践指南2017年由日本食道协会编辑：第2部分。
DOI：
10.1007/s10388-018-0642-8
发表时间：
2019-01
期刊：
Esophagus : official journal of the Japan Esophageal Society
影响因子：
--
作者：
Kitagawa Y;Uno T;Oyama T;Kato K;Kato H;Kawakubo H;Kawamura O;Kusano M;Kuwano H;Takeuchi H;Toh Y;Doki Y;Naomoto Y;Nemoto K;Booka E;Matsubara H;Miyazaki T;Muto M;Yanagisawa A;Yoshida M
通讯作者：
Yoshida M
影响因子：
--
作者：
Ensrud, Kristine E.;Ewing, Susan K.;Cummings, Steven R.
通讯作者：
Cummings, Steven R.