Toward improved models of human cancer.

Toward improved models of human cancer.
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改进人类癌症模型。

DOI:
10.1063/5.0030534
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发表时间:
2021-03
期刊:
影响因子:
6
通讯作者:
Welm AL
Welm AL
中科院分区:
工程技术2区
文献类型:
--
作者:
Welm BE;Vaklavas C;Welm AL

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Human cancer is a complex and heterogeneous collection of diseases that kills more than 18 million people every year worldwide. Despite advances in detection, diagnosis, and treatments for cancers, new strategies are needed to combat deadly cancers. Models of human cancer continue to evolve for preclinical research and have culminated in patient-derived systems that better represent the diversity and complexity of cancer. Still, no model is perfect. This Perspective attempts to address ways that we can improve the clinical translatability of models used for cancer research, from the point of view of researchers who mainly conduct cancer studies in vivo.
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