Validation, visibility, vagueness and variation: A qualitative assessment of existing veterinary guidelines for antimicrobial use in cattle and sheep in the UK.
Validation, visibility, vagueness and variation: A qualitative assessment of existing veterinary guidelines for antimicrobial use in cattle and sheep in the UK.
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DOI：
10.1371/journal.pone.0294733
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发表时间：
2023
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
在兽医中，抗菌剂是治疗和控制动物细菌性疾病的必不可少的药物。鼓励在食用动物中谨慎使用它们，以减少抗菌素耐药性的发展和传播。已经制定了负责任使用抗菌剂的国家和国际指南，作为指导和合理化兽医的抗菌剂处方决定和农民的使用决定的工具。然而，对于这些现有的指导方针是否符合目的，人们几乎没有什么了解。因此，这项研究严格评估了英国128个反刍动物使用抗菌剂的兽医指南，遵循既定的定性方法。调查结果揭示了四个相关的主题：确认兽医是处方者，负责任的使用现实的可见性，解释的模糊性和指导行为的变化。这些主题包括兽医的角色和责任，以及开处方情景的现实，以及与指南内的特殊性和指南之间的差异有关的关切。为指导和支持今后制定准则而提出的建议包括：建立特定物种和特定疾病的准则；扩大准则以包括疾病预防措施，包括解决解释含糊和促进一致性的定义；鼓励制定实践一级准则，以认可协作和自主权；促进利益攸关方之间积极工作，以协调优先事项和信息传递。
Antimicrobials are essential in veterinary medicine to treat and control bacterial disease in animals. Their prudent use in food-producing animals has been encouraged to reduce the development and spread of antimicrobial resistance. National and international guidelines for responsible antimicrobial use have been developed as tools to guide and rationalise antimicrobial prescribing decisions by veterinarians and usage decisions by farmers. Yet, there is little understanding of whether these existing guidelines are fit for purpose. Accordingly, this study rigorously assessed 128 veterinary guidelines for antimicrobial use in ruminants in the UK, following established qualitative methodologies. Findings revealed four pertinent themes: validation of the veterinarian as the prescriber, visibility of responsible use realities, vagueness in interpretation and variation in directing behaviour. These themes encompassed the roles and responsibilities of the veterinarian and the realities of prescribing scenarios, alongside concerns relating to the specificity within and variation between guidelines. Resultant recommendations to inform and support the future development of guidelines include establishing species-specific and disease-specific guidelines, expanding guidelines to include disease prevention measures, including definitions to resolve vagueness and promoting congruence in interpretation, encouraging the development of practice-level guidelines to endorse collaboration and ownership, and fostering active working between stakeholders to align priorities and messaging.
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影响因子：
7.2
作者：
Akl, Elie A.;Guyatt, Gordon H.;Schuenemann, Holger J.
通讯作者：
Schuenemann, Holger J.
概述和评估欧洲小动物兽医实践中合理抗菌剂使用的现有指南。
DOI：
10.3390/antibiotics10040409
发表时间：
2021-04-09
期刊：
Antibiotics (Basel, Switzerland)
影响因子：
--
作者：
Allerton F;Prior C;Bagcigil AF;Broens E;Callens B;Damborg P;Dewulf J;Filippitzi ME;Carmo LP;Gómez-Raja J;Harpaz E;Mateus A;Nolff M;Phythian CJ;Timofte D;Zendri F;Jessen LR
通讯作者：
Jessen LR
影响因子：
3.2
作者：
Dalglish SL;Khalid H;McMahon SA
通讯作者：
McMahon SA
影响因子：
2.4
作者：
Braun, Virginia;Clarke, Victoria
通讯作者：
Clarke, Victoria
影响因子：
2.2
作者：
Currie, Kay;King, Caroline;Flowers, Paul
通讯作者：
Flowers, Paul