Method for 3D Airway Topology Extraction

Method for 3D Airway Topology Extraction
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3D气道拓扑提取方法

DOI:
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发表时间:
2015
期刊:
Comput. Math. Methods Medicine
影响因子:
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通讯作者:
B. Rosenhahn
B. Rosenhahn
中科院分区:
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文献类型:
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作者:
R. Grothausmann;M. Kellner;M. Heidrich;R. Lorbeer;T. Ripken;H. Meyer;M. Kuehnel;M. Ochs;B. Rosenhahn

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在肺中,传导气道世代的数量以及分叉模式在不同物种之间有所不同,并显示出与疾病或基因变异有关的特定特征。本文提出了一种利用扫描激光光学层析(SLOT)层析图表征小鼠气道树拓扑结构的方法。它被用来测试两种类型的小鼠之间的区别,基于检测到的差异,他们的传导气道模式。基于这些层析图中气道的分割,计算出体积骨架的主生成树。所得图谱结构用于区分野生型和表面活性剂蛋白(SP-D)缺失敲除小鼠。
In lungs the number of conducting airway generations as well as bifurcation patterns varies across species and shows specific characteristics relating to illnesses or gene variations. A method to characterize the topology of the mouse airway tree using scanning laser optical tomography (SLOT) tomograms is presented in this paper. It is used to test discrimination between two types of mice based on detected differences in their conducting airway pattern. Based on segmentations of the airways in these tomograms, the main spanning tree of the volume skeleton is computed. The resulting graph structure is used to distinguish between wild type and surfactant protein (SP-D) deficient knock-out mice.
DOI: 10.1364/oe.19.005419
发表时间: 2011-03-14
期刊: OPTICS EXPRESS
影响因子: 3.8
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发表时间: 2004-12-01
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