Estimation of the number of injecting drug users attending an outreach syringe-exchange program and infection with human immunodeficiency virus (HIV) and hepatitis C virus: the AjUDE-Brasil project
Estimation of the number of injecting drug users attending an outreach syringe-exchange program and infection with human immunodeficiency virus (HIV) and hepatitis C virus: the AjUDE-Brasil project
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估计参加外展注射器交换计划的注射吸毒者人数以及感染人体免疫缺陷病毒（HIV）和丙型肝炎病毒的人数：AjUDE-巴西项目
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
Denise Doneda
中科院分区：
文献类型：
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作者：
W. Caiaffa;S. Mingoti;F. Proietti;A. Carneiro;Rodrigo Carazolli Silva;A. C. Lopes;Denise Doneda
本研究估计了街头注射毒品使用者（IDU）的数量的吸毒者交换计划（SEP）谁感染了人类免疫缺陷病毒（HIV）和丙型肝炎病毒（HCV）的客户。采用双样本捕获-再捕获法。第一份记录列出了1998年4月1日至5月1日期间接受注射器交换外展服务的所有接受采访的注射吸毒者;第二份记录涉及1998年5月2日至6月6日期间接受外展服务的注射吸毒者。采集血样用于HIV和HCV血清学检测。分析采用随时间变化的捕获概率模型。我们在第一次捕获中采访了55名注射吸毒者，在第二次捕获中采访了99名注射吸毒者; 17名参与了两个样本。估计有317名注射吸毒者参加了SEP（95%置信区间[CI] 235-467）。根据HIV（47.7%）和HCV（53.1%）的总体血清阳性率，估计151名注射吸毒者感染了HIV（95%CI 112-223），168名注射吸毒者感染了HCV（95%CI 125-248）。与艾滋病毒和丙型肝炎病毒血清阳性总数估计数相关的注射吸毒者的计数为SEPs提供了一个强有力的工具，以帮助监测注射吸毒者的数量，规划供应，并组织对现有卫生设施的艾滋病毒和丙型肝炎病毒护理的新需求。
This study estimated the number of street injecting drug user (IDU) clients of a syringe-exchange program (SEP) who were infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). A two-sample capture-recapture method was carried out. The first capture listed all interviewed IDUs outreached for syringe exchange from April 1 to May 1, 1998; the second capture involved those outreached from May 2 to June 6, 1998. Blood spots were collected for HIV and HCV serologies. Analysis used captured probability model varying with time. We interviewed 55 IDUs in the first capture and 99 in the second; 17 participated in both samples. An estimate of 317 IDUs attending the SEP was obtained (95% confidence interval [CI] 235–467). Based on the overall seroprevalence rates for HIV (47.7%) and HCV (53.1%), it was estimated that 151 IDUs were HIV infected (95% CI 112–223) and 168 (95% CI 125–248) were HCV infected. Enumeration of IDUs associated with estimates of the total number of HIV and HCV seropositives provide a powerful tool for SEPs to help monitor the number of IDUs, to plan for provisions, and to organize the new demands on existing health facilities for HIV and HCV care.
影响因子：
12.7
作者：
Garfein, RS;Vlahov, D;Nelson, KE
通讯作者：
Nelson, KE
影响因子：
120.7
作者：
Thomas, DL;Astemborski, J;Vlahov, D
通讯作者：
Vlahov, D