CalDAG-GEFI and platelet activation.
CalDAG-GEFI and platelet activation.
复制标题
CalDAG-GEFI 和血小板活化。
DOI:
10.3109/09537101003639931
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发表时间:
2010
期刊:
影响因子:
3.3
通讯作者:
Bergmeier W
中科院分区:
文献类型:
--
作者:
Stefanini L;Bergmeier W
Rapid activation of platelets at sites of vascular injury is a critical event in thrombosis and hemostasis. Here, we review recent findings, which a) identified CalDAG-GEFI (RasGRP2) at the nexus of the rapid, Ca2+-dependent platelet activation, b) demonstrated a complex synergy between signaling provided by CalDAG-GEFI, protein kinase C, and the Gi-coupled receptor for ADP, P2Y12, and c) suggested CalDAG-GEFI as a novel target for anti-platelet therapy.
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影响因子:
20.3
作者:
Bernardi, B;Guidetti, GF;Torti, M
通讯作者:
Torti, M
影响因子:
4.8
作者:
Clyde-Smith, J;Silins, G;Hancock, JF
通讯作者:
Hancock, JF
DOI:
10.1073/pnas.0812822106
发表时间:
2009-02-24
影响因子:
11.1
作者:
Crittenden, Jill R.;Cantuti-Castelvetri, Ippolita;Graybiel, Ann M.
通讯作者:
Graybiel, Ann M.
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56.9
作者:
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通讯作者:
Stone, JC
影响因子:
20.3
作者:
Kuijpers, Taco W.;van de Vijver, Edith;Baas, Frank
通讯作者:
Baas, Frank