Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity.
Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity.
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DOI:
10.1186/s12859-018-2164-8
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发表时间:
2018-05-02
影响因子:
3
通讯作者:
Gagneux S
中科院分区:
文献类型:
--
作者:
Menardo F;Loiseau C;Brites D;Coscolla M;Gygli SM;Rutaihwa LK;Trauner A;Beisel C;Borrell S;Gagneux S
Large sequence datasets are difficult to visualize and handle. Additionally, they often do not represent a random subset of the natural diversity, but the result of uncoordinated and convenience sampling. Consequently, they can suffer from redundancy and sampling biases. Here we present Treemmer, a simple tool to evaluate the redundancy of phylogenetic trees and reduce their complexity by eliminating leaves that contribute the least to the tree diversity. Treemmer can reduce the size of datasets with different phylogenetic structures and levels of redundancy while maintaining a sub-sample that is representative of the original diversity. Additionally, it is possible to fine-tune the behavior of Treemmer including any kind of meta-information, making Treemmer particularly useful for empirical studies. The online version of this article (10.1186/s12859-018-2164-8) contains supplementary material, which is available to authorized users.
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影响因子:
5.8
作者:
Li, Heng
通讯作者:
Li, Heng
影响因子:
5.8
作者:
Li, WZ;Jaroszewski, L;Godzik, A
通讯作者:
Godzik, A
影响因子:
3
作者:
Huson, Daniel H.;Richter, Daniel C.;Rausch, Christian;Dezulian, Tobias;Franz, Markus;Rupp, Regula
通讯作者:
Rupp, Regula
影响因子:
5.8
作者:
Neher, Richard A.;Bedford, Trevor
通讯作者:
Bedford, Trevor
影响因子:
30.8
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Comas, Inaki;Coscolla, Mireia;Luo, Tao;Borrell, Sonia;Holt, Kathryn E.;Kato-Maeda, Midori;Parkhill, Julian;Malla, Bijaya;Berg, Stefan;Thwaites, Guy;Yeboah-Manu, Dorothy;Bothamley, Graham;Mei, Jian;Wei, Lanhai;Bentley, Stephen;Harris, Simon R.;Niemann, Stefan;Diel, Roland;Aseffa, Abraham;Gao, Qian;Young, Douglas;Gagneux, Sebastien
通讯作者:
Gagneux, Sebastien