Effects of Ca2+ and ionophore A23187 on protein synthesis in intact rabbit reticulocytes.
Effects of Ca2+ and ionophore A23187 on protein synthesis in intact rabbit reticulocytes.
复制标题
Ca2 和离子载体 A23187 对完整兔网织红细胞蛋白质合成的影响。
DOI:
10.1016/0020-711x(87)90055-3
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发表时间:
1991
期刊:
影响因子:
--
通讯作者:
Brostrom,CO
中科院分区:
文献类型:
--
作者:
Wong,WL;Brostrom,MA;Brostrom,CO
1. Amino acid incorporation in intact rabbit reticulocytes was unaffected by depletion of Ca2+ with EGTA. 2. The Ca2+ ionophore A23187 strongly inhibited incorporation in reticulocytes incubated in 1 mM Ca2+ but not in EGTA. Polysomal profiles and average ribosomal transit times of cells treated with Ca2+ ionophore at 1 mM Ca2+ were characteristic of translational elongation block. 3. The behavior of reticulocytes with respect to Ca2+ and A23187 contrasts with that of nucleated cells possessing endoplasmic reticulum in which protein synthesis is inhibited at translational initiation by either Ca2+ depletion or by exposure to Ca2+ ionophore.
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DOI:
--
发表时间:
1989
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Mackie,KP;Nairn,AC;Hampel,G;Lam,G;Jaffe,EA
通讯作者:
Jaffe,EA
影响因子:
18.2
作者:
Brostrom,CO;Brostrom,MA
通讯作者:
Brostrom,MA
DOI:
10.1016/s0021-9258(18)45377-x
发表时间:
1987-12
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Angus C. Nairnz;C. Palfrey
通讯作者:
Angus C. Nairnz;C. Palfrey
DOI:
10.1016/s0021-9258(18)48002-7
发表时间:
1987-07
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
H. Palfrey;A. Nairn;L. Muldoon;M. Villereal
通讯作者:
H. Palfrey;A. Nairn;L. Muldoon;M. Villereal
DOI:
--
发表时间:
1989
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Brostrom,CO;Chin,KV;Wong,WL;Cade,C;Brostrom,MA
通讯作者:
Brostrom,MA