Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation.
Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation.
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作者：
Kwak K;Yu B;Lewandowski RJ;Kim DH
随着现代成像技术的快速发展，微创消融手术已经成为手术切除肿瘤的流行替代方案。目前在临床实践中提供的肿瘤消融方式包括微波消融、射频消融、冷冻消融、高强度聚焦超声和不可逆电穿孔。冷冻消融是一种非热消融方法，越来越多地用于治疗各种实体瘤。冷冻消融与基于热的消融技术的累积比较数据（例如，射频和微波消融）显示出上级肿瘤反应和更快的恢复时间。不断发展的研究已经证明，纳米载体可以作为冷冻消融治疗、成像引导和治疗剂的共递送的优异催化剂，用于具有免疫调节的癌症的微创、精确和完全治疗。这篇综述文章重点介绍了冷冻消融术在临床实践中的现状，考虑了增强冷冻消融术治疗效果的机会，并讨论了该领域的新研究，包括治疗诊断纳米颗粒介导的冷冻疗法和基于冷冻的联合免疫疗法。
With rapid advances in modern imaging, minimally invasive ablative procedures have emerged as popular alternatives to surgical removal of tumors. Tumor ablation modalities currently offered in clinical practice include microwave ablation, radiofrequency ablation, cryoablation, high-intensity focused ultrasound, and irreversible electroporation. Cryoablation, a non-heat-based method of ablation, is increasingly being used for treating various solid tumors. Accumulated comparative data of cryoablation versus heat-based ablation techniques (e.g., radiofrequency and microwave ablation) shows superior tumor response and quicker recovery time. Evolving research has demonstrated that nanocarriers may serves as excellent catalysts for the cryoablation therapy, imaging guidance, and the co-delivery of therapeutics for minimally invasive, precise, and complete treatment of cancer with immune modulation. This review article focuses on the current status of cryoablation in clinical practice, considers opportunities for enhancing therapeutic outcomes from cryoablation, and discusses new research in the field, including theranostic nanoparticles-mediated cryotherapy and combinational cryo-based immunotherapies.
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影响因子：
1.6
作者：
Chaudhry A;Grechushkin V;Hoshmand M;Kim CW;Pena A;Huston B;Chaya Y;Bilfinger T;Moore W
通讯作者：
Moore W
DOI：
10.1002/advs.202002425
发表时间：
2021-03
期刊：
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
影响因子：
--
作者：
Chang T;Zhao G
通讯作者：
Zhao G
影响因子：
3.1
作者：
Baust, John G.;Snyder, Kristi K.;Baust, John M.
通讯作者：
Baust, John M.
影响因子：
2.9
作者：
Alkhalifa H;Mohammed F;Taurin S;Greish K;Taha S;Fredericks S
通讯作者：
Fredericks S
用氧化石墨烯纳米片探测冰形成的临界核尺寸
影响因子：
64.8
作者：
Bai, Guoying;Gao, Dong;Wang, Jianjun
通讯作者：
Wang, Jianjun