Recommendation to reconsider examining cannabis subtypes together due to opposing effects on brain, cognition and behavior.
Recommendation to reconsider examining cannabis subtypes together due to opposing effects on brain, cognition and behavior.
复制标题
DOI:
10.1016/j.neubiorev.2017.05.025
复制
发表时间:
2017-09
影响因子:
8.2
通讯作者:
Feldstein Ewing SW
中科院分区:
文献类型:
--
作者:
Rømer Thomsen K;Callesen MB;Feldstein Ewing SW
Cannabis use represents a major public health issue throughout the globe. Yet, we still lack the most fundamental knowledge on long-term effects of cannabis on neural, cognitive, and behavioral function. Part of this stems from how cannabis has been measured historically. To this end, most empirical examinations of cannabis have consolidated all types of cannabis collectively. However, this approach obscures differences in how cannabinoids operate. In this commentary, we address the contrasting properties of tetrahydrocannabinol (THC) and cannabidiol (CBD) and their opposing effects on cognitive function. In addition, we address the increase in cannabis potency throughout the past two decades and how that impacts generalizability of early data to evaluations of contemporary public health. We underscore the urgent need for future research to disaggregate examination of THC from CBD, along with the importance of measuring cannabis potency to more effectively unravel its influence on cognitive function and other health issues.
登录
查看更多内容
影响因子:
--
作者:
Fusar-Poli, Paolo;Crippa, Jose A.;McGuire, Philip K.
通讯作者:
McGuire, Philip K.
影响因子:
7.6
作者:
Winton-Brown, Toby T.;Allen, Paul;McGuire, Philip K.
通讯作者:
McGuire, Philip K.
影响因子:
6.8
作者:
Leweke FM;Piomelli D;Pahlisch F;Muhl D;Gerth CW;Hoyer C;Klosterkötter J;Hellmich M;Koethe D
通讯作者:
Koethe D
影响因子:
4.1
作者:
Englund, Amir;Morrison, Paul D.;Kapur, Shitij
通讯作者:
Kapur, Shitij
影响因子:
7.3
作者:
Laprairie, R. B.;Bagher, A. M.;Denovan-Wright, E. M.
通讯作者:
Denovan-Wright, E. M.