Effect of a long-acting somatostatin analogue (SMS 201-995) in a patient with pancreatic cholera.

Effect of a long-acting somatostatin analogue (SMS 201-995) in a patient with pancreatic cholera.
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长效生长抑素类似物 (SMS 201-995) 对胰腺霍乱患者的作用。

DOI:
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发表时间:
1985
影响因子:
158.5
通讯作者:
R. Jensen
R. Jensen
中科院分区:
医学1区
文献类型:
--
作者:
P. Maton;T. O'dorisio;B. Howe;K. Mcarthur;J. Howard;J. Cherner;T. Malarkey;M. Collen;J. Gardner;R. Jensen

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胰腺霍乱的特征是水样腹泻、低钾血症和酸中毒1,在大多数情况下是由于胰腺的非β胰岛细胞肿瘤分泌血管活性肠多肽(VIP)和肽组氨酸异亮氨酸2。当这种肿瘤局限于胰腺时,手术切除可能会治愈,在转移性疾病患者中,链脲佐菌素可以减小肿瘤的大小并控制肿瘤。3各种其他药物-皮质类固醇,4锂,5甲氧氯普胺,6可乐定,7三氟拉嗪,8和吲哚美辛9-也可以偶尔减少腹泻,并且据报道,连续静脉输注生长抑素也可以减少腹泻和降低血浆浓度。
PANCREATIC cholera is characterized by watery diarrhea, hypokalemia, and acidosis1 and in most cases is due to a non-β-islet-cell tumor of the pancreas that secretes vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine.2 When such tumors are localized to the pancreas, surgical resection may produce a cure, and in patients with metastatic disease streptozocin may reduce the tumor's size and control the symptoms.3 A variety of other agents — corticosteroids,4 lithium,5 metoclopramide,6 clonidine,7 trifluoperazine,8 and indomethacin9 — may also occasionally reduce the diarrhea, and continuous intravenous infusion of somatostatin has also been reported to reduce diarrhea and decrease plasma concentrations . . .
可乐定和利达脒可抑制肺癌患者的水样腹泻。
DOI: 10.7326/0003-4819-96-3-323
发表时间: 1982
影响因子: 39.2
作者:
McArthur,KE;Anderson,DS;Durbin,TE;Orloff,MJ;Dharmsathaphorn,K
通讯作者: Dharmsathaphorn,K
DOI: 10.1016/0024-3205(84)90594-0
发表时间: 1984
期刊: Life sciences
影响因子: 6.1
作者:
DePalatis,LR;Khorram,O;Ho,RH;Negro-Vilar,A;McCann,SM
通讯作者: McCann,SM