The association between frequency of e-cigarette use and long-term smoking cessation outcomes among treatment-seeking smokers receiving a behavioral intervention.

The association between frequency of e-cigarette use and long-term smoking cessation outcomes among treatment-seeking smokers receiving a behavioral intervention.
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DOI:
10.1016/j.drugalcdep.2020.108394
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发表时间:
2021-01-01
影响因子:
4.2
通讯作者:
Bricker JB
Bricker JB
中科院分区:
医学2区
文献类型:
--
作者:
Watson NL;Mull KE;Bricker JB

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越来越多的文献表明,在普通成年人中,每天(而非非每天)使用电子烟与戒掉可燃香烟的几率更高有关。然而,尚不清楚这些发现是否适用于接受行为干预的寻求治疗的吸烟者。我们的主要目的是研究在接受行为戒烟干预的寻求治疗的吸烟者中,使用电子烟的频率是否与随后的戒烟有关。参与者(N = 2637)参加了一项基于网络的吸烟治疗的随机对照试验,报告了他们在基线、3个月和6个月时使用电子烟的情况。根据电子烟的使用情况创建了三个组:(1)非用户,(2)间歇性用户和(3)每日用户。主要结果是完全病例,自我报告的12个月时30天的点流行禁欲。与不使用电子烟的人相比,每天使用电子烟的人明显不太可能戒烟(21.39%比29.68%;p = 0.006)。间歇性使用者的戒烟率(24.56%)与非使用者没有显著差异(p = 0.092)。尼古丁依赖调节了结果,在尼古丁依赖性较低的吸烟者中,使用电子烟(间歇性或每天)的人比不使用电子烟的人更不可能戒烟;这些差异在高度尼古丁依赖者中不显著。事后分析表明,在基线后开始每天使用电子烟,而不是在基线时每天使用电子烟,与较低的戒烟几率有关。在寻求治疗的吸烟者中,每日使用电子烟可能与戒烟几率较低有关,特别是在尼古丁依赖性较低和开始干预后开始每日使用电子烟的吸烟者中。
A growing body of literature suggests daily, but not non-daily, e-cigarette use is associated with greater odds of quitting combustible cigarettes in the general adult population. However, it is unknown if these findings generalize to treatment-seeking smokers who are receiving a behavioral intervention. Our primary aim was to examine whether frequency of e-cigarette use was associated with subsequent cessation among treatment-seeking smokers who are receiving a behavioral smoking cessation intervention. Participants (N = 2637) enrolled in a RCT of web-based smoking treatments reported their use of e-cigarettes at baseline, 3-, and 6-months. Three groups were created based on e-cigarette use: (1) non-users, (2) intermittent users, and (3) daily users. The primary outcome was complete-case, self-reported 30-day point prevalence abstinence at 12 months. Compared to non-users, daily e-cigarette users were significantly less likely to be abstinent (21.39 % vs. 29.68 %; p = .006). Quit rates for intermittent users (24.56 %) were not significantly different from non-users (p = .092). Nicotine dependence moderated the results such that among smokers with low nicotine dependence, those who used e-cigarettes (intermittently or daily) were less likely to quit than non-users; these differences were not significant among those with high nicotine dependence. Post hoc analyses indicated that initiating daily e-cigarette use after baseline, but not daily e-cigarette use at baseline, was associated with lower odds of cessation. Daily e-cig use may be associated with lower odds of quitting smoking among treatment-seeking smokers, particularly among those with lower nicotine dependence and who initiate daily use after beginning an intervention.
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