Mortality risk associated with combinations of loneliness and social isolation. Findings from The Irish Longitudinal Study on Ageing (TILDA).
Mortality risk associated with combinations of loneliness and social isolation. Findings from The Irish Longitudinal Study on Ageing (TILDA).
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DOI：
10.1093/ageing/afab004
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发表时间：
2021-06-28
期刊：
影响因子：
6.7
通讯作者：
Nolan A
中科院分区：
文献类型：
--
作者：
Ward M;May P;Normand C;Kenny RA;Nolan A
为应对2019年冠状病毒病疫情而采取的社交距离及类似措施大大增加了老年人的孤独感和社交孤立感。因此，了解孤独和死亡率之间的关系至关重要。我们研究了孤独和社会孤立的组合，使用一种名为社会不对称的指标，是否与死亡风险增加有关。样本来自爱尔兰老龄化纵向研究的参与者，这是一个具有全国代表性的社区居住老年人样本，年龄≥50岁。调查数据与官方死亡登记记录相关联。考克斯比例风险回归和竞争风险生存分析被用来研究社会不对称性与全因和特定原因死亡率之间的关系。在四个社会不对称组中，和谐低孤独（低孤独，低隔离）包括35.5%的参与者; 26.4%是和谐高孤独（高孤独，高隔离）; 19.2%是不和谐的健壮（低孤独，高隔离）和18.9%是不和谐的敏感（高孤独，低隔离）。与一致性低孤独组相比，一致性高孤独组（风险比[HR] = 1.43，95%置信区间[CI]：1.09-1.87）和不一致性稳健组（HR = 1.37，95% CI：1.04-1.81）的死亡风险增加。一致的高孤独组由于循环系统疾病而死亡的风险增加（子分布风险比= 1.52，95%CI：1.03-2.25）。我们发现，社会不对称预测死亡率超过7年的随访期。我们的研究结果证实，主观孤独和客观社会隔离之间的不匹配，以及孤独和社会隔离的结合，与全因死亡风险增加有关。
Social distancing and similar measures in response to the coronavirus disease 2019 pandemic have greatly increased loneliness and social isolation among older adults. Understanding the association between loneliness and mortality is therefore critically important. We examined whether combinations of loneliness and social isolation, using a metric named social asymmetry, was associated with increased mortality risk. The sample was derived from participants in The Irish Longitudinal Study on Ageing, a nationally representative sample of community-dwelling older adults aged ≥50. Survey data were linked to official death registration records. Cox proportional hazards regressions and competing risk survival analyses were used to examine the association between social asymmetry and all-cause and cause-specific mortality. Of four social asymmetry groups, concordant low lonely (low loneliness, low isolation) included 35.5% of participants; 26.4% were concordant high lonely (high loneliness, high isolation); 19.2% were discordant robust (low loneliness, high isolation) and 18.9% discordant susceptible (high loneliness, low isolation). The concordant high lonely (hazard ratio [HR] = 1.43, 95% confidence interval [CI]: 1.09–1.87) and discordant robust (HR = 1.37, 95% CI: 1.04–1.81) groups had an increased mortality risk compared to those in the concordant low lonely group. The concordant high lonely group had an increased risk of mortality due to diseases of the circulatory system (sub-distribution hazard ratio = 1.52, 95% CI: 1.03–2.25). We found that social asymmetry predicted mortality over a 7-year follow-up period. Our results confirm that a mismatch between subjective loneliness and objective social isolation, as well as the combination of loneliness and social isolation, were associated with an increased all-cause mortality risk.
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影响因子：
6.7
作者：
Jarach, Carlotta Micaela;Tettamanti, Mauro;D'avanzo, Barbara
通讯作者：
D'avanzo, Barbara
影响因子：
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作者：
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通讯作者：
Stephenson, David
DOI：
10.1093/geronb/gbt121
发表时间：
2014-03-01
影响因子：
6.2
作者：
Burholt, Vanessa;Scharf, Thomas
通讯作者：
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影响因子：
4
作者：
McHugh, J. E.;Kenny, R. A.;Kee, F.
通讯作者：
Kee, F.
DOI：
10.1158/1078-0432.ccr-11-2097
发表时间：
2012-04-15
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
Dignam JJ;Zhang Q;Kocherginsky M
通讯作者：
Kocherginsky M