Somatic and anxiety symptoms of depression are associated with disability in late life depression.
Somatic and anxiety symptoms of depression are associated with disability in late life depression.
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DOI：
10.1080/13607863.2019.1597013
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发表时间：
2020-08
影响因子：
3.4
通讯作者：
Mackin, R. Scott
中科院分区：
文献类型：
--
作者：
Morin, Ruth T.;Nelson, Craig;Bickford, David;Insel, Philip S.;Mackin, R. Scott
评估患有晚年抑郁症的老年人样本中抑郁症的躯体和焦虑症状与功能障碍的关系。对 78 名 65-88 岁患有重度抑郁症的老年人的数据进行了分析。对 24 项汉密尔顿抑郁评定量表 (HDRS) 中的躯体症状和焦虑症状进行汇总，以创建衡量这些症状严重程度的变量。抑郁症的其他症状也使用 HDRS 的其余项目进行评估。使用功能合并症指数（FCI）评估当前的身体健康负担。使用晚年功能和残疾仪器（LLFDI）总限制评分来测量残疾程度。进行线性回归分析以评估躯体和焦虑症状与独立于其他因素的残疾的关联。该模型解释了 26.6% 的残疾方差 (F(6,51) = 3.1, p = .01)。抑郁症的躯体症状（B=−1.9，p=.004）和焦虑症状（B=−3.7，p=.04）与残疾显着相关。其他抑郁症状和身体疾病负担与残疾无关。在患有重度抑郁症的老年人中，抑郁症的躯体症状和焦虑症状与残疾有关。识别和治疗缓解这些症状可能会改善老年抑郁症患者的功能结果。
To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression. Data were analyzed from 78 older adults aged 65-88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of these symptoms. Other symptoms of depression were also assessed using the remaining items of the HDRS. Current physical health burden was assessed using the Functional Comorbidity Index (FCI). Disability was measured with the Late Life Function and Disability Instrument (LLFDI) total limitation score. A linear regression analysis was performed to assess the association of somatic and anxiety symptoms with disability independent of other factors. The model accounted for 26.6% of variance in disability, (F(6,51) = 3.1, p = .01). Somatic (B=−1.9, p=.004) and anxiety (B=−3.7, p=.04) symptoms of depression were significantly associated with disability. Other depressive symptoms and physical illness burden were not associated with disability. In older adults with major depression, somatic and anxiety symptoms of depression are associated with disability. Identification and treatment to remission of these symptoms may improve functional outcomes among older depressed adults.
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影响因子：
6.6
作者：
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通讯作者：
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