Tracheal epithelium releases a vascular smooth muscle relaxant factor: demonstration by bioassay.
Tracheal epithelium releases a vascular smooth muscle relaxant factor: demonstration by bioassay.
复制标题
气管上皮释放血管平滑肌松弛因子：生物测定证明。
DOI：
10.1016/0014-2999(86)90586-8
复制
发表时间：
1986
影响因子：
5
通讯作者：
I. Sahin
中科院分区：
文献类型：
--
作者：
M. Ilhan;I. Sahin
乙酰胆碱对苯肾上腺素预收缩的兔主动脉摩擦条无舒张作用。当从上皮完整的豚鼠气管中取出相同的条时，乙酰胆碱产生缓慢发展的松弛，其被阿托品拮抗，但不被普萘洛尔、吲哚美辛、茶碱或氢醌拮抗。乙酰胆碱对摩擦气管上皮的RASR无松弛作用。结果表明，乙酰胆碱从气管上皮释放血管平滑肌松弛因子。
Acetylcholine caused no relaxation of a rubbed strip from rabbit aorta (RASR) which was precontracted with phenyleprinne. When the same strip was taken from epithelium-intact guinea-pig trachea, acetylcholine produced a slow-developing relaxation which was antagonized by atropine but not by propranolol, indomethacin, theophylline or hydroquinone. RASR was not relaxed by acetylcholine when it was taken from epithelium-rubbed trachea. The results indicate that acetylcholine releases vascular smooth muscle relaxant factor from tracheal epithelium.
呼吸道上皮抑制支气管平滑肌张力。
DOI：
10.1152/jappl.1985.58.3.834
发表时间：
1985
期刊：
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子：
--
作者：
Flavahan,NA;Aarhus,LL;Rimele,TJ;Vanhoutte,PM
通讯作者：
Vanhoutte,PM