The sleep-deprived human brain.

The sleep-deprived human brain.
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DOI:
10.1038/nrn.2017.55
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发表时间:
2017-07
期刊:
Nature reviews. Neuroscience
影响因子:
--
通讯作者:
Walker MP
Walker MP
中科院分区:
其他
文献类型:
--
作者:
Krause AJ;Simon EB;Mander BA;Greer SM;Saletin JM;Goldstein-Piekarski AN;Walker MP

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睡眠不足如何影响我们的大脑?与睡眠的好处相比,探索睡眠不足影响的框架相对缺乏。重要的是,睡眠剥夺(SD)的影响并不仅仅反映了睡眠的缺乏及其带来的好处;相反,它们反映了几个其他因素的后果,包括延长的觉醒。本文以神经影像学研究为重点,综述了SD对注意力和工作记忆、积极和消极情绪以及海马学习的影响。我们探讨了这些证据如何告知我们对与SD相关的认知和情感变化的机械理解,以及它提供的关于与睡眠中断相关的临床状况的见解。
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep deprivation (SD) do not simply reflect the absence of sleep and the benefits attributed to it; rather, they reflect the consequences of several additional factors, including extended wakefulness. With a focus on neuroimaging studies, we review the consequences of SD on attention and working memory, positive and negative emotion, and hippocampal learning. We explore how this evidence informs our mechanistic understanding of the known changes in cognition and emotion associated with SD, and the insights it provides regarding clinical conditions associated with sleep disruption.
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