Relationship Between Autonomic Nervous System Activity and Axial Length in Children.
Relationship Between Autonomic Nervous System Activity and Axial Length in Children.
复制标题
自主神经系统活动与儿童轴向长度之间的关系。
DOI：
10.12659/msm.939451
复制
发表时间：
2023-05-13
期刊：
影响因子：
--
通讯作者：
Xiang Y
中科院分区：
文献类型：
--
作者：
Li M;Xu Q;Yan X;Wang J;Xiang Y
本研究的目的是比较轴性近视眼和非轴性近视眼的自主神经系统活性，并探讨儿童自主神经系统活性与眼轴长度（AL）之间的关系。78名儿童的78只眼被纳入本研究。使用自动瞳孔测量仪记录静态和动态瞳孔反应，包括瞳孔直径、潜伏期和瞳孔收缩和扩张速度，以评估自主神经系统活动。使用IOL-Master器械测量AL。在静态瞳孔反应方面，中间视觉条件下的瞳孔直径（1坎德拉/平方米）（PD 1）（4.06±0.64 vs 3.80±0.87 mm，P=0.045）和低明视条件下的瞳孔直径（10坎德拉/m2）（PD 10）（3.40±0.49 vs 3.22±0.66 mm，P=0.046）轴性近视眼显著大于非轴性近视眼。在动态瞳孔反应方面，轴性近视眼的瞳孔收缩速度（Vel-C）（5.93±0.89 vs 6.75±1.60 mm/s，P=0.019）和瞳孔扩张速度（Vel-D）（2.28±0.38 vs 2.89±1.17 mm/s，P=0.002）明显低于非轴性近视眼。PD 1、PD 10与AL呈正相关，Vel-C、Vel-D与AL呈负相关（P均<0.05）。与非轴性近视相比，轴性近视的自主神经系统活动显着降低，并且自主神经系统活动与儿童AL呈显着负相关。轴性近视自主神经系统活动的减少可能导致儿童轴性近视眼眼轴过度延长。
The aim of this work was to compare autonomic nervous system activity between eyes with axial and non-axial myopia and to investigate the relationship between autonomic nervous system activity and axial length (AL) in children. Seventy-eight eyes of 78 children were included in this study. Static and dynamic pupillary responses, including pupil diameter, latency, and velocity of pupil contraction and dilation, were recorded using automatic pupillometry to evaluate autonomic nervous system activity. AL was measured using the IOL-Master device. In terms of static pupillary responses, the pupil diameter at mesopic condition (1 candelas/m2) (PD1) (4.06±0.64 vs 3.80±0.87 mm, P=0.045) and pupil diameter at low photopic condition (10 candelas/m2) (PD10) (3.40±0.49 vs 3.22±0.66 mm, P=0.046) were significantly larger in axial myopic eyes than in non-axial myopic eyes. In terms of dynamic pupillary responses, velocity of pupil contraction (Vel-C) (5.93±0.89 vs 6.75±1.60 mm/s, P=0.019) and velocity of pupil dilation (Vel-D) (2.28±0.38 vs 2.89±1.17 mm/s, P=0.002) were significantly slower in axial myopic eyes than in non-axial myopic eyes. Moreover, PD1 and PD10 were significantly and positively associated with AL, while Vel-C and Vel-D were significantly and negatively associated with AL (all P<0.05). There was significant decrease in autonomic nervous system activity in axial myopia compared with non-axial myopia, and autonomic nervous system activity was significantly and negatively associated with AL in children. Decreases in autonomic nervous system activity in axial myopia may contribute to the excessive axial elongation in pediatric axial myopia.
DOI：
10.3390/ijerph19052942
发表时间：
2022-03-03
影响因子：
--
作者：
Lin SY;Su HR;Lo CC;Yeh SM;Lee CH;Wu R;Lin FC;Chu YW;Huang SY
通讯作者：
Huang SY