Cognitive decline in Alzheimer disease

Cognitive decline in Alzheimer disease
复制标题

阿尔茨海默病的认知能力下降

DOI:
--
复制
发表时间:
2007
期刊:
影响因子:
9.9
通讯作者:
M. Freedman
M. Freedman
中科院分区:
医学1区
文献类型:
--
作者:
Y. Kaufman;D. Anaki;M. Binns;M. Freedman

文献摘要

参考文献

被引文献

相似文献

目的:评价生活质量(QOL)、精神信仰和宗教信仰对阿尔茨海默病(AD)认知衰退进展速度的影响。方法:在这项纵向研究中,我们招募了70例可能患有AD的患者。使用简易精神状态检查来监测认知能力下降的速度。宗教虔诚度和灵性度是用标准化的量表来衡量的,这些量表评估灵性、宗教虔诚度以及组织和私人的宗教活动。我们同时对影响认知能力下降的因素进行了多元线性回归分析。结果:在控制了基线认知水平、年龄、性别和教育水平后,较慢的认知下降速度与较高的灵性水平(p < 0.05)和私人宗教活动(p < 0.005)相关。这些变量占总方差的17% [F(11,58) = 2.24, p < 0.05]。认知能力下降率与生活质量无相关性。结论:高水平的灵性和私人宗教活动与阿尔茨海默病的缓慢进展有关,但与生活质量无关。
Objective: To assess effects of quality of life (QOL), spirituality, and religiosity on rate of progression of cognitive decline in Alzheimer disease (AD). Methods: In this longitudinal study, we recruited 70 patients with probable AD. The Mini-Mental State Examination was used to monitor the rate of cognitive decline. Religiosity and spirituality were measured using standardized scales that assess spirituality, religiosity, and organizational and private religious practices. We conducted a simultaneous multiple linear regression analysis for factors contributing to rate of cognitive decline. Results: After controlling for baseline level of cognition, age, sex, and education, a slower rate of cognitive decline was associated with higher levels of spirituality (p < 0.05) and private religious practices (p < 0.005). These variables accounted for 17% of the total variance [F(11,58) = 2.24, p < 0.05]. There was no correlation between rate of cognitive decline and QOL. Conclusion: Higher levels of spirituality and private religious practices, but not quality of life, are associated with slower progression of Alzheimer disease.
宗教信仰与有症状的艾滋病毒感染男同性恋者的情感和免疫状态有关。
DOI: 10.1016/s0022-3999(98)00078-6
发表时间: 1999
影响因子: 4.7
作者:
Woods,TE;Antoni,MH;Ironson,GH;Kling,DW
通讯作者: Kling,DW
DOI: 10.1093/geronj/46.2.s103
发表时间: 1991
期刊: Journal of gerontology
影响因子: --
作者:
Taylor,RJ;Chatters,LM
通讯作者: Chatters,LM
DOI: 10.1093/geronb/52b.6.s306
发表时间: 1997-11-01
影响因子: 6.2
作者:
Idler, EL;Kasl, SV
通讯作者: Kasl, SV
DOI: 10.1176/ajp.149.12.1693
发表时间: 1992
期刊: The American journal of psychiatry
影响因子: --
作者:
Koenig,HG;Cohen,HJ;Blazer,DG;Pieper,C;Meador,KG;Shelp,F;Goli,V;DiPasquale,B
通讯作者: DiPasquale,B
DOI: 10.1126/science.3399889
发表时间: 1988-07
期刊: Science
影响因子: 56.9
作者:
J. House;Karl R. Landis;Debra J Umberson
通讯作者: J. House;Karl R. Landis;Debra J Umberson