Three-dimensional manometry of the upper esophageal sphincter in swallowing and nonswallowing tasks.
Three-dimensional manometry of the upper esophageal sphincter in swallowing and nonswallowing tasks.
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DOI：
10.1002/lary.25957
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发表时间：
2016-11
期刊：
影响因子：
2.6
通讯作者：
McCulloch, Timothy M.
中科院分区：
文献类型：
--
作者：
Meyer, Jacob P.;Jones, Corinne A.;Walczak, Chelsea C.;McCulloch, Timothy M.
高分辨率测压(HRM)有助于识别无序吞咽模式和量化咽部和上食道括约肌(UES)的生理。HRM受到单向传感器和压力周向平均的限制，导致对来自不对称咽部解剖的压力的理解不完善。本研究的目的是从不同的轴向同时评估UES压力。案件系列。对8名健康受试者进行了三维HRM检查，以评估静息状态、Valsalva动作时和吞水时UES周围的压力模式。多变量方差分析显示，静息时周向对压力有显著的主效应(P<；.001)；UES的前部和后部的压力比侧部的压力大。在Valsalva动作中，没有发现方向对压力的显著主要影响。在吞咽5毫升水丸的过程中，周向对UES压力下降前的压力有显著的主效应(P=.001)，在UES开放时(P=.01)和UES关闭时(P<；.001)。在UES压力下降之前(P=.032)和在UES关闭时(P<；.001)，沿垂直轴的传感器水平对压力也有显著的主效应。在所有吞咽事件中，前压和后压再次大于侧压。这些结果证实了UES的压力因其周向起始点的不同而有显著差异，大部分总压产生于前部和后部。更好地了解三维空间中的UES压力可以导致对咽部和UES功能障碍的更复杂的治疗。4.喉镜，126：2539-2545,2016
High‐resolution manometry (HRM) is useful in identifying disordered swallowing patterns and quantifying pharyngeal and upper esophageal sphincter (UES) physiology. HRM is limited by unidirectional sensors and circumferential averaging of pressures, resulting in an imperfect understanding of pressure from asymmetrical pharyngeal anatomy. This study aims to evaluate UES pressures simultaneously from different axial directions. Case series. Three‐dimensional HRM was performed on eight healthy subjects to evaluate circumferential UES pressure patterns at rest, during the Valsalva maneuver, and during water swallowing. Multivariate analysis of the variance revealed a significant main effect of circumferential direction on pressure while at rest (P < .001); pressure was greater in the anterior and posterior portions of the UES versus lateral portions. A significant main effect of direction on pressure was not found during the Valsalva maneuver. During swallowing of a 5‐mL water bolus, circumferential direction had a significant main effect on pressure immediately before UES pressure dropped (P = .001), while the UES was open (P = .01) and at UES closure (P < .001). There was also a significant main effect of sensor level along the vertical axis on pressure immediately before UES pressure dropped (P = .032) and at UES closure (P < .001). Anterior and posterior pressures were again greater than lateral pressures at all swallowing events. These results confirm that UES pressures vary significantly based on their circumferential origin, with the majority of the total pressure generated in anterior and posterior regions. Improved understanding of UES pressure in a three‐dimensional space can lead to more sophisticated treatments for pharyngeal and UES dysfunction. 4. Laryngoscope, 126:2539–2545, 2016
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DOI：
10.1177/000348941011900602
发表时间：
2010-06
期刊：
The Annals of otology, rhinology, and laryngology
影响因子：
--
作者：
McCulloch TM;Hoffman MR;Ciucci MR
通讯作者：
Ciucci MR
DOI：
10.1152/ajpgi.00510.2005
发表时间：
2006-05-01
影响因子：
4.5
作者：
Ghosh, SK;Pandolfino, JE;Kahrilas, PJ
通讯作者：
Kahrilas, PJ
影响因子：
1.4
作者：
SCHNEIDER, I;POTOTSCHNIG, C;ECKEL, HE
通讯作者：
ECKEL, HE
影响因子：
1.4
作者：
Munoz, Amanda A.;Shapiro, Jo;Bhattacharyya, Neil
通讯作者：
Bhattacharyya, Neil
影响因子：
15.9
作者：
WELCH, RW;LUCKMANN, K;GATES, GA
通讯作者：
GATES, GA