Effect of co-ingestion of amino acids with rice on glycaemic and insulinaemic response
Effect of co-ingestion of amino acids with rice on glycaemic and insulinaemic response
复制标题
氨基酸与大米共同摄入对血糖和胰岛素反应的影响
DOI：
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发表时间：
2015
影响因子：
3.6
通讯作者：
C. Henry
中科院分区：
文献类型：
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作者：
Y. Soong;Joseph Lim;Lijuan Sun;C. Henry
摘要高血糖指数（GI）和高血糖反应（GR）食物如白色米饭的摄入与2型糖尿病的发生有关。先前的研究已经报道了单个氨基酸降低富含碳水化合物食物的GR的能力。由于氨基酸的苦味，它们很少被用来减少GR。我们现在报告使用一种美味的、预先形成的氨基酸混合物，以鸡肉香精的形式。16名健康中国男性在食用白色米饭前15或30 min，将68或136 ml氨基酸混合物与米饭一起食用。在空腹时和进食后每15分钟测量餐后血糖和血浆胰岛素浓度，直到进食白色米饭后60分钟。随后的血液样本，采取在30分钟的时间间隔，直到210分钟。共摄入68毫升的氨基酸混合物与白色大米产生的最佳结果，在降低峰值血糖和GR的白色大米，而不增加胰岛素血症的反应。据推测，氨基酸混合物引发β细胞胰岛素分泌和外周组织葡萄糖摄取。使用即饮型氨基酸混合物可能是降低亚洲高GI大米饮食消费的一种有用策略。
Abstract Consumption of high glycaemic index (GI) and glycaemic response (GR) food such as white rice has been implicated in the development of type 2 diabetes. Previous studies have reported the ability of individual amino acids to reduce GR of carbohydrate-rich foods. Because of the bitter flavour of amino acids, they have rarely been used to reduce GR. We now report the use of a palatable, preformed amino acid mixture in the form of essence of chicken. In all, sixteen healthy male Chinese were served 68 or 136 ml amino acid mixture together with rice, or 15 or 30 min before consumption of white rice. Postprandial blood glucose and plasma insulin concentrations were measured at fasting and every 15 min after consumption of the meal until 60 min after the consumption of the white rice. Subsequent blood samples were taken at 30-min intervals until 210 min. The co-ingestion of 68 ml of amino acid mixture with white rice produced the best results in reducing the peak blood glucose and GR of white rice without increasing the insulinaemic response. It is postulated that amino acid mixtures prime β-cell insulin secretion and peripheral tissue uptake of glucose. The use of ready-to-drink amino acid mixtures may be a useful strategy for lowering the high-GI rice diets consumed in Asia.
影响因子：
5
作者：
R. Hanson;R. Pratley;C. Bogardus;K. Narayan;J. Roumain;G. Imperatore;A. Fagot-Campagna;D. Pettitt;Peter H. Bennett;W. Knowler
通讯作者：
R. Hanson;R. Pratley;C. Bogardus;K. Narayan;J. Roumain;G. Imperatore;A. Fagot-Campagna;D. Pettitt;Peter H. Bennett;W. Knowler
影响因子：
--
作者：
Villegas, Raquel;Liu, Simin;Shu, Xiao Ou
通讯作者：
Shu, Xiao Ou