PROTOGENE: turning amino acid alignments into bona fide CDS nucleotide alignments.
PROTOGENE: turning amino acid alignments into bona fide CDS nucleotide alignments.
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DOI:
10.1093/nar/gkl170
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发表时间:
2006-07-01
影响因子:
14.9
通讯作者:
Notredame C
中科院分区:
文献类型:
--
作者:
Moretti S;Reinier F;Poirot O;Armougom F;Audic S;Keduas V;Notredame C
We describe Protogene, a server that can turn a protein multiple sequence alignment into the equivalent alignment of the original gene coding DNA. Protogene relies on a pipeline where every initial protein sequence is BLASTed against RefSeq or NR. The annotation associated with potential matches is used to identify the gene sequence. This gene sequence is then aligned with the query protein using Exonerate in order to extract a coding nucleotide sequence matching the original protein. Protogene can handle protein fragments and will return every CDS coding for a given protein, even if they occur in different genomes. Protogene is available from .
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影响因子:
14.9
作者:
Finn, Robert D.;Mistry, Jaina;Schuster-Bockler, Benjamin;Griffiths-Jones, Sam;Hollich, Volker;Lassmann, Timo;Moxon, Simon;Marshall, Mhairi;Khanna, Ajay;Durbin, Richard;Eddy, Sean R.;Sonnhammer, Erik L. L.;Bateman, Alex
通讯作者:
Bateman, Alex
影响因子:
3
作者:
Slater GS;Birney E
通讯作者:
Birney E
影响因子:
14.9
作者:
Wheeler, David L.;Barrett, Tanya;Yaschenko, Eugene
通讯作者:
Yaschenko, Eugene
影响因子:
3
作者:
Bininda-Emonds OR
通讯作者:
Bininda-Emonds OR
影响因子:
3
作者:
Stocsits RR;Hofacker IL;Fried C;Stadler PF
通讯作者:
Stadler PF