Prophylaxis and treatment of COVID-19 related venous thromboembolism.
Prophylaxis and treatment of COVID-19 related venous thromboembolism.
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DOI：
10.1080/00325481.2021.1891788
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发表时间：
2021-08
影响因子：
4.2
通讯作者：
Klok FA
中科院分区：
文献类型：
--
作者：
Kaptein FHJ;Stals MAM;Huisman MV;Klok FA
COVID-19 pneumonia has been associated with high rates of thrombo-embolic complications, mostly venous thromboembolism (VTE), which is thought to be a combination of conventional VTE and in situ immunothrombosis in the pulmonary vascular tree. The incidence of thrombotic complications is dependent on setting (intensive care unit (ICU) versus general ward) and the threshold for performing diagnostic tests (screening versus diagnostic algorithms triggered by symptoms). Since these thrombotic complications are associated with in-hospital mortality, all current guidelines and consensus papers propose pharmacological thromboprophylaxis in all hospitalized patients with COVID-19. Several trials are ongoing to study the optimal intensity of anticoagulation for this purpose. As for the management of thrombotic complications, treatment regimens from non-COVID-19 guidelines can be adapted, with choice of anticoagulant drug class dependent on the situation. Parenteral anticoagulation is preferred for patients on ICUs or with impending clinical deterioration, while oral treatment can be started in stable patients. This review describes current knowledge on incidence and pathophysiology of COVID-19 associated VTE and provides an overview of guideline recommendations on thromboprophylaxis and treatment of established VTE in COVID-19 patients.
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影响因子：
8
作者：
Di Nisio M;Potere N;Candeloro M;Spacone A;Pieramati L;Ferrandu G;Rizzo G;La Vella M;Di Carlo S;Cibelli D;Parruti G;Levi M;Porreca E
通讯作者：
Porreca E
影响因子：
3.3
作者：
Amgalan, Ariunzaya;Othman, Maha
通讯作者：
Othman, Maha
影响因子：
24.3
作者：
Ende-Verhaar, Yvonne M.;Cannegieter, Suzanne C.;Klok, Frederikus A.
通讯作者：
Klok, Frederikus A.
影响因子：
158.5
作者：
Ackermann, Maximilian;Verleden, Stijn E.;Jonigk, Danny
通讯作者：
Jonigk, Danny
DOI：
10.1183/16000617.0287-2020
发表时间：
2020-09-30
期刊：
European respiratory review : an official journal of the European Respiratory Society
影响因子：
--
作者：
Bai C;Chotirmall SH;Rello J;Alba GA;Ginns LC;Krishnan JA;Rogers R;Bendstrup E;Burgel PR;Chalmers JD;Chua A;Crothers KA;Duggal A;Kim YW;Laffey JG;Luna CM;Niederman MS;Raghu G;Ramirez JA;Riera J;Roca O;Tamae-Kakazu M;Torres A;Watkins RR;Barrecheguren M;Belliato M;Chami HA;Chen R;Cortes-Puentes GA;Delacruz C;Hayes MM;Heunks LMA;Holets SR;Hough CL;Jagpal S;Jeon K;Johkoh T;Lee MM;Liebler J;McElvaney GN;Moskowitz A;Oeckler RA;Ojanguren I;O'Regan A;Pletz MW;Rhee CK;Schultz MJ;Storti E;Strange C;Thomson CC;Torriani FJ;Wang X;Wuyts W;Xu T;Yang D;Zhang Z;Wilson KC
通讯作者：
Wilson KC