Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project.
Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project.
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DOI：
10.1186/ar2956
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发表时间：
2010
影响因子：
4.9
通讯作者：
Jordan JM
中科院分区：
文献类型：
--
作者：
Callahan LF;Shreffler J;Siaton BC;Helmick CG;Schoster B;Schwartz TA;Chen JC;Renner JB;Jordan JM
对来自约翰斯顿县骨关节炎项目的2，627名年龄≥ 45岁的非洲裔美国人和白人成年人样本进行横断面分析，我们研究了教育程度与放射学膝关节骨关节炎和症状性膝关节骨关节炎患病率之间的关系。通过性别分层逻辑回归模型评估教育与骨关节炎结局之间的年龄和种族调整相关性，并对身体质量指数、膝关节损伤、吸烟、饮酒和职业因素进行调整。在对所有参与者的分析中，低教育程度（<12年）与四种膝关节骨关节炎结局（单侧和双侧放射学和症状性骨关节炎）的患病率较高相关。通过使用完全校正的模型，与受教育程度较高（≥ 12年）的女性相比，受教育程度低的女性患放射学膝关节骨关节炎的几率高50%，症状性膝关节骨关节炎的几率高65%。在绝经后妇女的亚组中，这些关联往往较弱，但几乎不受激素替代疗法调整的影响。通过使用完全校正的模型，受教育程度低的男性患有症状性膝关节骨关节炎的几率高出85%，但与放射学膝关节骨关节炎的相关性可以用年龄来解释。在调整已知的危险因素后，教育程度作为社会经济地位的指标，与男性和女性的症状性膝关节骨关节炎以及女性的放射学膝关节骨关节炎相关。
Applying a cross-sectional analysis to a sample of 2,627 African-American and Caucasian adults aged ≥ 45 years from the Johnston County Osteoarthritis Project, we studied the association between educational attainment and prevalence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis. Age- and race-adjusted associations between education and osteoarthritis outcomes were assessed by gender-stratified logistic regression models, with additional models adjusting for body mass index, knee injury, smoking, alcohol use, and occupational factors. In an analysis of all participants, low educational attainment (<12 years) was associated with higher prevalence of four knee osteoarthritis outcomes (unilateral and bilateral radiographic and symptomatic osteoarthritis). Women with low educational attainment had 50% higher odds of having radiographic knee osteoarthritis and 65% higher odds of symptomatic knee osteoarthritis compared with those with higher educational attainment (≥ 12 years), by using fully adjusted models. In the subset of postmenopausal women, these associations tended to be weaker but little affected by adjustment for hormone replacement therapy. Men with low educational attainment had 85% higher odds of having symptomatic knee osteoarthritis by using fully adjusted models, but the association with radiographic knee osteoarthritis was explained by age. After adjustment for known risk factors, educational attainment, as an indicator of socioeconomic status, is associated with symptomatic knee osteoarthritis in both men and women and with radiographic knee osteoarthritis in women.
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影响因子：
5
作者：
FELDMAN, JJ;MAKUC, DM;CORNONIHUNTLEY, J
通讯作者：
CORNONIHUNTLEY, J
DOI：
10.1002/art.11200
发表时间：
2003-08-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Jacobi, CE;Mol, GD;Van den Bos, GAM
通讯作者：
Van den Bos, GAM
影响因子：
4.7
作者：
Jordan, JM;Linder, GF;Fryer, JG
通讯作者：
Fryer, JG
影响因子：
7.7
作者：
Dalstra, JAA;Kunst, AE;Mackenbach, JP
通讯作者：
Mackenbach, JP
影响因子：
5.9
作者：
Finley, C;Gregg, EW;Gay, E
通讯作者：
Gay, E