Non-protein coding RNA biomarkers and differential expression in cancers: a review.
Non-protein coding RNA biomarkers and differential expression in cancers: a review.
复制标题
DOI:
10.1186/1756-9966-27-19
复制
发表时间:
2008-07-16
期刊:
影响因子:
--
通讯作者:
D'Urso OF
中科院分区:
文献类型:
--
作者:
Mallardo M;Poltronieri P;D'Urso OF
In these years a huge number of human transcripts has been found that do not code for proteins, named non-protein coding RNAs. In most cases, small (miRNAs, snoRNAs) and long RNAs (antisense RNA, dsRNA, and long RNA species) have many roles, functioning as regulators of other mRNAs, at transcriptional and post-transcriptional level, and controlling protein ubiquitination and degradation. Various species of npcRNAs have been found differentially expressed in different types of cancer. This review discusses the published data and new results on the expression of a subset of npcRNAs. These results underscore the complexity of the RNA world and provide further evidence on the involvement of functional RNAs in cancer cell growth control.
登录
查看更多内容
影响因子:
64.5
作者:
Cawley, S;Bekiranov, S;Gingeras, TR
通讯作者:
Gingeras, TR
影响因子:
4.5
作者:
Cai, XZ;Hagedorn, CH;Cullen, BR
通讯作者:
Cullen, BR
影响因子:
8
作者:
Anderson, CJ;Hoare, SF;Keith, WN
通讯作者:
Keith, WN
影响因子:
4.6
作者:
Brito, Glauber Costa;Fachel, Angela A.;Reis, Eduardo M.
通讯作者:
Reis, Eduardo M.
影响因子:
64.8
作者:
Denli, AM;Tops, BBJ;Hannon, GJ
通讯作者:
Hannon, GJ