Age-related impairment on a forced-choice version of the Mnemonic Similarity Task.
Age-related impairment on a forced-choice version of the Mnemonic Similarity Task.
复制标题
在助记符相似性任务的强制选择版本上与年龄相关的障碍。
DOI：
10.1037/bne0000180
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发表时间：
2017-03
影响因子：
1.9
通讯作者：
Stark CE
中科院分区：
文献类型：
--
作者：
Huffman DJ;Stark CE
我们实验室以前的研究表明，健康的老年人在记忆相似性任务（MST）中对以前观察过的物体和类似的诱饵物体进行记忆区分的能力受损。这些研究使用了旧/类似/新或旧/新测试格式。强制选择测试格式（例如，“你在编码阶段看到物体A或物体A'了吗？”）依赖于与旧/新测试格式不同的假设（例如，“您在编码阶段看到此对象了吗？”）;因此，从这些方法中收集的证据将支持健康老龄化伴随着MST表现受损的结论。与我们的假设相一致，健康的老年人表现出受损的性能上被迫选择测试格式，需要区分目标和类似的诱惑。我们还测试了MST上与年龄相关的损伤可以在全局匹配计算框架内建模的假设。我们发现，降低模型中成功特征编码的概率会导致与健康老年人经验数据相似的变化。总的来说，我们的行为结果扩展到强迫选择测试格式的发现，健康的老龄化伴随着受损的能力，区分目标和类似的诱惑，我们的建模结果表明，编码刺激功能的可能性降低是一个候选机制，在健康老龄化的记忆变化。我们还讨论了全球匹配模型的能力，以解释在其他研究中使用的变体记忆相似性任务的发现。
Previous studies from our lab have indicated that healthy older adults are impaired in their ability to mnemonically discriminate between previously viewed objects and similar lure objects in the Mnemonic Similarity Task (MST). These studies have used either old/similar/new or old/new test formats. The forced-choice test format (e.g., “Did you see object A or object A’ during the encoding phase?”) relies on different assumptions than the old/new test format (e.g., “Did you see this object during the encoding phase?”); hence, converging evidence from these approaches would bolster the conclusion that healthy aging is accompanied by impaired performance on the MST. Consistent with our hypothesis, healthy older adults exhibited impaired performance on a forced-choice test format that required discriminating between a target and a similar lure. We also tested the hypothesis that age-related impairments on the MST could be modeled within a global matching computational framework. We found that decreasing the probability of successful feature encoding in the models caused changes that were similar to the empirical data in healthy older adults. Collectively, our behavioral results extend to the forced-choice test format the finding that healthy aging is accompanied by an impaired ability to discriminate between targets and similar lures, and our modeling results suggest that a diminished probability of encoding stimulus features is a candidate mechanism for memory changes in healthy aging. We also discuss the ability of global matching models to account for findings in other studies that have used variants on mnemonic similarity tasks.
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DOI：
10.1101/lm.038141.115
发表时间：
2015-08
期刊：
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子：
--
作者：
Loiotile RE;Courtney SM
通讯作者：
Courtney SM
影响因子：
3.5
作者：
Norman, Kenneth A.
通讯作者：
Norman, Kenneth A.
影响因子：
3.7
作者：
Bennett, Ilana J.;Huffman, Derek J.;Stark, Craig E. L.
通讯作者：
Stark, Craig E. L.
影响因子：
1.7
作者：
Migo, Ellen;Montaldi, Daniela;Mayes, Andrew
通讯作者：
Mayes, Andrew
影响因子：
2.6
作者：
Khoe, W;Kroll, NEA;Knight, RT
通讯作者：
Knight, RT