Function of the atrioventricular node considered on the basis of observed histology and fine structure.
Function of the atrioventricular node considered on the basis of observed histology and fine structure.
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根据观察到的组织学和精细结构考虑房室结的功能。
DOI：
10.1016/s0735-1097(85)80411-3
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发表时间：
1985
影响因子：
24
通讯作者：
Woods,WT
中科院分区：
文献类型：
--
作者：
Sherf,L;James,TN;Woods,WT
采用房室结动脉直接灌注法，对20只幼犬心脏房室结区域进行体外研究。细胞内穿刺微电极记录了所有20只狗的局部跨膜动作电位。这些结果与20只狗中7只狗的连续切片组织学研究相关联，以表征一个较小的区域，该区域为其他4只狗的心脏电镜检查提供了解剖指导。本报告描述了发现的各种特定细胞，包括它们的细胞内内容和组织，以及它们的细胞间连接的性质。在这些发现的基础上，我们将房室结细胞随意分为两种类型，移行细胞和P细胞，尽管我们确定了三种不同的移行细胞。第一组细胞主要位于房室结的外缘，细胞长而细长，具有间隙连接或连接的大轮廓。第二组和第三组移行细胞构成房室结主体的大部分，呈椭圆形或椭圆形，含有较少和较小的间隙连接。房室结的P细胞与窦房结中大量存在的P细胞相似；它们主要出现在房室结和他束的交界处。根据这些精细的结构特征和观察到的组织结构和跨膜动作电位，对局部电生理事件的临床和实验方面进行了讨论。
From the hearts of 20 young dogs, the region of the atrioventricular (AV) node was studied in vitro utilizing direct perfusion of the AV node artery. Intracellular impalement with microelectrodes provided records of local transmembrane action potentials in all 20 dogs. These were correlated with serial section histologic studies in 7 of the 20 dogs to characterize a smaller region that served as an anatomic guide for electron microscopic examination in 4 other dog hearts.This report describes the variety of specific cells found, including their intracellular content and organization, as well as the nature of their intercellular junctions. On the basis of these findings, AV nodal cells were arbitrarily divided into two types, transitional cells and P cells, although three somewhat different groups of tran- sitional cells were identified. The first group, found principally at the outer margin of the AV node, has long and slender cells that exhibit large profiles of gap junctions or nexuses. The second and third groups of transitional cells, which constitute most of the body of the AV node, are oblong or oval and contain fewer and smaller gap junctions. P cells of the AV node resemble those more abundantly present in the sinus node; they are found principally at the junction of the AV node and His bundle. On the basis of these fine structural features and the histologic organization and transmembrane action potentials observed, clinical and experimental aspects of the local electrophysiologic events are discussed.
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二度房室传导阻滞。
影响因子：
37.8
作者：
D. Zipes
通讯作者：
D. Zipes
暴露犬近端 AV 传导系统以进行电生理学研究。
影响因子：
3.3
作者：
M. Elizari;K. Greenspan;C. Fisch
通讯作者：
C. Fisch
DOI：
10.2170/jjphysiol.30.529
发表时间：
1980
期刊：
The Japanese journal of physiology
影响因子：
--
作者：
S. Kokubun;M. Nishimura;A. Noma;H. Irisawa
通讯作者：
H. Irisawa
狗完全性房室传导阻滞时逃逸节律起源部位的相关电生理学和解剖学研究
影响因子：
20.1
作者：
T. James;J. Isobe;And Ferdinand Urthaler
通讯作者：
And Ferdinand Urthaler
心房波前方向对兔离体心脏 A-V 结传输的影响。
影响因子：
20.1
作者：
M. Janse
通讯作者：
M. Janse