Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex.

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex.
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DOI:
10.1038/nrn2402
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发表时间:
2008-07
影响因子:
34.7
通讯作者:
Yuste, Rafael
Yuste, Rafael
中科院分区:
医学1区
文献类型:
--
作者:
Ascoli, Giorgio A.;Alonso-Nanclares, Lidia;Anderson, Stewart A.;Barrionuevo, German;Benavides-Piccione, Ruth;Burkhalter, Andreas;Buzsaki, Gyoergy;Cauli, Bruno;DeFelipe, Javier;Fairen, Alfonso;Feldmeyer, Dirk;Fishell, Gord;Fregnac, Yves;Freund, Tamas F.;Gardner, Daniel;Gardner, Esther P.;Goldberg, Jesse H.;Helmstaedter, Moritz;Hestrin, Shaul;Karube, Fuyuki;Kisvarday, Zoltan F.;Lambolez, Bertrand;Lewis, David A.;Marin, Oscar;Markram, Henry;Munoz, Alberto;Packer, Adam;Petersen, Carl C. H.;Rockland, Kathleen S.;Rossier, Jean;Rudy, Bernardo;Somogyi, Peter;Staiger, Jochen F.;Tamas, Gabor;Thomson, Alex M.;Toledo-Rodriguez, Maria;Wang, Yun;West, David C.;Yuste, Rafael

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神经科学从各种各样的神经元中产生了大量的数据。神经元分类系统对于组织这些数据和从中获得的知识至关重要。分类取决于明确识别区分一种类型神经元与另一种类型神经元的特征。当研究皮质中间神经元时,其中固有的问题尤其严重。为了解决这个问题,我们召集了一组有代表性的研究人员,就一组术语达成一致,以描述大脑皮层GABA能中间神经元的解剖学,生理学和分子特征。由此产生的术语可能会为这些复杂和异质细胞的未来分类提供一块垫脚石。一致采用这一举措对于这一举措的成功至关重要,我们还鼓励更广泛的科学界积极参与这一项目的动态发展。
Neuroscience produces a vast amount of data from an enormous diversity of neurons. A neuronal classification system is essential to organize such data and the knowledge that is derived from them. Classification depends on the unequivocal identification of the features that distinguish one type of neuron from another. The problems inherent in this are particularly acute when studying cortical interneurons. To tackle this, we convened a representative group of researchers to agree on a set of terms to describe the anatomical, physiological and molecular features of GABAergic interneurons of the cerebral cortex. The resulting terminology might provide a stepping stone towards a future classification of these complex and heterogeneous cells. Consistent adoption will be important for the success of such an initiative, and we also encourage the active involvement of the broader scientific community in the dynamic evolution of this project.
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