Nonsteroidal anti-inflammatory drugs. Caution still indicated.

Nonsteroidal anti-inflammatory drugs. Caution still indicated.
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非甾体抗炎药。

DOI:
10.1001/jama.251.10.1301
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发表时间:
1984
期刊:
JAMA
影响因子:
--
通讯作者:
W. Henrich
W. Henrich
中科院分区:
--
文献类型:
--
作者:
R. Schrier;W. Henrich

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Nonsteroidal anti-inflammatory drugs (NSAIDs) have become a major component of modern clinical therapeutics. These drugs are popular because of their effectiveness in a wide range of disorders commonly encountered in medical practice, including arthritis, tendonitis, orthopedic injuries, and even dysmenorrhea. While nephrologists would not debate that NSAIDs are clinically effective, the widespread use of these agents has resulted in a growing recognition that the drugs are capable of causing acute deterioration in renal function. Many nephrologists report that NSAIDs now rank behind only aminoglycosides as a cause of nephrotoxic acute renal failure (ARF) in their practices. Exact incidence data are not yet available; it is this important and pertinent issue that Fox and Jick1address in the current article on NSAIDs and renal failure. Of the several adverse effects these agents may have on renal function, two are most commonly recognized. The first is a reversible decrement in renal
抑制前列腺素合成的药物对肾脏的影响。
DOI: 10.1038/ki.1980.179
发表时间: 1980
影响因子: 19.6
作者:
Dunn,MJ;Zambraski,EJ
通讯作者: Zambraski,EJ