A Self-Adaptive Differential Evolution Algorithm for Parameters Identification of Stochastic Genetic Regulatory Networks with Random Delays
A Self-Adaptive Differential Evolution Algorithm for Parameters Identification of Stochastic Genetic Regulatory Networks with Random Delays
复制标题
随机时滞随机遗传调控网络参数识别的自适应差分进化算法
DOI:
10.1007/s13369-013-0803-y
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发表时间:
2013-09
影响因子:
2.9
通讯作者:
Zhang, Wenbing
中科院分区:
文献类型:
--
作者:
Zhao, Shuguang;Zhu, Wu;Liu, Yuying;Zhang, Wenbing
The study of identifying the biological systems from the available data, especially the parameters identification of genetic regulatory networks (GRNs), has received increasing interests in the recent years. In this paper, an improved differential evolution (DE) algorithm, population adaptive differential evolution (PADE), is proposed to solve global optimization problems with applications in identifying unknown parameters of a class of GRNs with random delays and stochastic perturbations. In the PADE, in order to enhance the global search ability and improve the convergent solutions, the process of adding and declining the number of population is designed according to the perturbation method and ranking technique, respectively. The PADE’s performance is compared with several well-known DE variants. The simulation results show that PADE is superior or comparable to the other algorithms and can be efficiently used to identify the unknown parameters of stochastic GRNs with random delays.
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