A genome-wide compilation of the two-component systems in Lotus japonicus.
A genome-wide compilation of the two-component systems in Lotus japonicus.
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DOI：
10.1093/dnares/dsp012
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发表时间：
2009-08
期刊：
影响因子：
--
通讯作者：
Mizuno T
中科院分区：
文献类型：
--
作者：
Ishida K;Niwa Y;Yamashino T;Mizuno T
双组分系统（TCS），或组氨酸-天冬氨酸磷酸化继电器，是进化上保守的共同信号转导机制，涉及原核生物和真核生物（包括植物）对环境刺激的各种细胞反应。在高等植物中，包括百脉根在内的豆科植物具有与固氮细菌进行有益共生的独特能力。我们以前提出了一个全基因组的编译列表的TCS相关的组成部分，中慢生根瘤菌loti，这是一个共生体，具体到L。Hagiwara等人，2004，DNA Res.，11，57-65）。为了获得对这种目前有吸引力的模式豆类的TCS的一般和具体见解，在这里，我们利用L.全基因组测序的努力，从全基因组的角度编译了尽可能多的与TCS相关的成分。他们几乎处于最后阶段。在目前的数据库（）中，发现L.至少有14个编码组氨酸激酶的基因，7个含组氨酸的磷酸传递素相关基因，7个A型反应调节因子（RR）相关基因，11个B型RR相关基因，以及5个与生物钟相关的假RR基因。这些结果表明，大多数L。在这项全基因组分析中，已经发现了与PTCS相关的基因，如果不是全部的话。在这里，这些TCS相关的L。将拟南芥与拟南芥进行比较。此外，还进行了一些关键性的实验，以进一步了解L。与细胞分裂素介导的信号转导和生物钟相关的基因。
The two-component systems (TCS), or histidine-to-aspartate phosphorelays, are evolutionarily conserved common signal transduction mechanisms that are implicated in a wide variety of cellular responses to environmental stimuli in both prokaryotes and eukaryotes including plants. Among higher plants, legumes including Lotus japonicus have a unique ability to engage in beneficial symbiosis with nitrogen-fixing bacteria. We previously presented a genome-wide compiled list of TCS-associated components of Mesorhizobium loti, which is a symbiont specific to L. japonicus (Hagiwara et al. 2004, DNA Res., 11, 57–65). To gain both general and specific insights into TCS of this currently attractive model legume, here we compiled TCS-associated components as many as possible from a genome-wide viewpoint by taking advantage that the efforts of whole genome sequencing of L. japonicus are almost at final stage. In the current database (), it was found that L. japonicus has, at least, 14 genes each encoding a histidine kinase, 7 histidine-containing phosphotransmitter-related genes, 7 type-A response regulator (RR)-related genes, 11 type-B RR-related genes, and also 5 circadian clock-associated pseudo-RR genes. These results suggested that most of the L. japonicus TCS-associated genes have already been uncovered in this genome-wide analysis, if not all. Here, characteristics of these TCS-associated components of L. japonicus were inspected, one by one, in comparison with those of Arabidopsis thaliana. In addition, some critical experiments were also done to gain further insights into the functions of L. japonicus TCS-associated genes with special reference to cytokinin-mediated signal transduction and circadian clock.
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影响因子：
11.6
作者：
Hosoda, K;Imamura, A;Yamazaki, T
通讯作者：
Yamazaki, T
影响因子：
4.9
作者：
Iwama, Ayako;Yamashino, Takafumi;Mizuno, Takeshi
通讯作者：
Mizuno, Takeshi
影响因子：
4.9
作者：
Ishida, Kai;Yamashino, Takafumi;Mizuno, Takeshi
通讯作者：
Mizuno, Takeshi
影响因子：
56.9
作者：
Mähönen, AP;Bishopp, A;Helariutta, Y
通讯作者：
Helariutta, Y
影响因子：
1.6
作者：
Hagiwara, Daisuke;Asano, Yoshihiro;Mizuno, Takeshi
通讯作者：
Mizuno, Takeshi