Uptake of colorectal cancer screening after mailed fecal immunochemical test (FIT) outreach in a newly eligible 45-49-year-old community health center population.
Uptake of colorectal cancer screening after mailed fecal immunochemical test (FIT) outreach in a newly eligible 45-49-year-old community health center population.
复制标题
DOI：
10.1007/s10552-023-01717-8
复制
发表时间：
2023-12
影响因子：
2.3
通讯作者：
Brenner, Alison T. T.
中科院分区：
文献类型：
--
作者：
O'Leary, Meghan C. C.;Reuland, Daniel S. S.;Correa, Sara Y. Y.;Moore, Alexis A. A.;Malo, Teri L. L.;Tan, Xianming;Rohweder, Catherine L. L.;Wheeler, Stephanie B. B.;Brenner, Alison T. T.
关键词：
我们根据2021年美国预防服务工作组的筛查建议，在45-49岁新符合结直肠癌（CRC）筛查条件的人群中评估了邮寄FIT干预后的粪便免疫化学试验（FIT）摄取。我们还测试了增强与普通邮件信封对FIT吸收的影响。2022年2月，我们向一家联邦合格健康中心（FHC）诊所的45-49岁符合条件的人邮寄了FIT。我们确定了在60天内完成FIT的比例。我们还进行了一项巢式随机试验，比较使用增强信封（填充有跟踪标签和彩色消息贴纸）与普通信封的吸收情况。最后，我们确定了任何形式的CRC筛查的变化（例如，FIT，结肠镜检查）在该年龄组的所有临床患者中（即，临床水平筛选）。我们向316名患者邮寄了FIT。样本特征：57%女性，58%非西班牙裔黑人，50%商业保险。总体而言，54/316（17.1%）例患者在60天内返回FIT，包括增强包膜组34/158（21.5%）例患者与普通包膜组20/158（12.7%）例患者（差异8.9个百分点，95% CI：0.6-17.2）。所有45-49岁人群的临床水平筛查增加了16.6个百分点（95%CI：10.9-22.3），从基线时的26.7%增加到6个月时的43.3%。在45-49岁的不同年龄段的CRC患者中，邮寄FIT干预后CRC筛查似乎增加。需要更大规模的研究来评估在这一年轻人群中CRC筛查的可接受性和完成情况。视觉上吸引人的邮件可以提高吸收时，实施邮寄干预措施。试验注册试验于2020年5月28日在ClinicalTrials.gov（标识符NCT 04406714）注册。
We assessed fecal immunochemical test (FIT) uptake following a mailed FIT intervention among 45–49-year-olds newly eligible for colorectal cancer (CRC) screening based on 2021 United States Preventive Services Task Force screening recommendations. We also tested the effect of an enhanced versus plain mailing envelope on FIT uptake. In February 2022 we mailed FITs to eligible 45–49-year-olds at one Federally Qualified Health Center (FQHC) clinic. We determined the proportion who completed FITs within 60 days. We also conducted a nested randomized trial comparing uptake using an enhanced envelope (padded with tracking label and colored messaging sticker) versus plain envelope. Finally, we determined the change in CRC screening by any modality (e.g., FIT, colonoscopy) among all clinic patients in this age group (i.e., clinic-level screening) between baseline and 6 months post-intervention. We mailed FITs to 316 patients. Sample characteristics: 57% female, 58% non-Hispanic Black, and 50% commercially insured. Overall, 54/316 (17.1%) returned a FIT within 60 days, including 34/158 (21.5%) patients in the enhanced envelope arm versus 20/158 (12.7%) in the plain envelope arm (difference 8.9 percentage points, 95% CI: 0.6–17.2). Clinic-level screening among all 45–49-year-olds increased 16.6 percentage points (95% CI: 10.9–22.3), from 26.7% at baseline to 43.3% at 6 months. CRC screening appeared to increase following a mailed FIT intervention among diverse FQHC patients aged 45–49. Larger studies are needed to assess acceptability and completion of CRC screening in this younger population. Visually appealing mailers may improve uptake when implementing mailed interventions. Trial registration The trial was registered on May 28, 2020 at ClinicalTrials.gov (identifier NCT04406714).
登录
查看更多内容
影响因子：
--
作者：
Malo TL;Correa SY;Moore AA;Ferrari RM;Leeman J;Brenner AT;Wheeler SB;Tan X;Reuland DS;Scaling Colorectal Cancer Screening Through Outreach, Referral, and Engagement (SCORE) Study Protocol Consortium
通讯作者：
Scaling Colorectal Cancer Screening Through Outreach, Referral, and Engagement (SCORE) Study Protocol Consortium
影响因子：
1.5
作者：
Greiner, Benjamin;Gandhi, Ronak;Hartwell, Micah
通讯作者：
Hartwell, Micah
影响因子：
5.7
作者：
Pignone, Michael;Lanier, Brennan;Olmstead, Todd
通讯作者：
Olmstead, Todd
影响因子：
5.5
作者：
Hall, Ingrid J.;Tangka, Florence K. L.;Breen, Nancy
通讯作者：
Breen, Nancy
影响因子：
5.5
作者：
Benavidez GA;Zgodic A;Zahnd WE;Eberth JM
通讯作者：
Eberth JM