Network analysis of 18 attention-deficit/hyperactivity disorder symptoms suggests the importance of "Distracted" and "Fidget" as central symptoms: Invariance across age, gender, and subtype presentations.
Network analysis of 18 attention-deficit/hyperactivity disorder symptoms suggests the importance of "Distracted" and "Fidget" as central symptoms: Invariance across age, gender, and subtype presentations.
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对 18 种注意力缺陷/多动障碍症状的网络分析表明，“分心”和“坐立不安”作为中心症状的重要性：跨年龄、性别和亚型表现的不变性
DOI：
10.3389/fpsyt.2022.974283
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发表时间：
2022
影响因子：
4.7
通讯作者：
Qian, Qiujin
中科院分区：
文献类型：
--
作者：
Liu, Lu;Wang, Yi;Chen, Wai;Gao, Yuan;Li, Haimei;Wang, Yufeng;Chan, Raymond C. K.;Qian, Qiujin
精神障碍的网络理论将精神症状概念化为相互因果作用的症状网络。本研究旨在探讨注意缺陷多动障碍（ADHD）儿童症状结构的网络分析。采用ADHD量表IV的18个项目对4,033名ADHD儿童青少年进行症状网络评估。通过检查中心性指标，包括强度，介数和接近度，以及可预测性和预期影响力（EI）来定量评估节点的重要性。此外，我们比较了不同亚组的网络结构，如ADHD亚型，性别和年龄组的特点，以评估其不变性。一个三因素的社区结构被确定为包括疏忽，多动和冲动集群。对于中心性指标，“分心”和“烦躁”的节点显示出较高的接近性和中间性，并代表了连接疏忽和多动/冲动域的桥梁。“细节”和“烦躁”分别是注意力不集中和多动/冲动领域最常见的认可症状。相反，“听”项目形成了一个外围节点，显示出与不注意集群内的所有其他项目的弱链接，和“损失”项目作为最不中心的节点，所有措施的中心性和低预测值。网络结构在性别、年龄和ADHD亚型/表现中相对不变。ADHD核心症状的18个项目似乎不等同和可互换。“分心”和“烦躁”应被视为中心或核心症状，以进行进一步评估和干预。这些症状的网络信息分化有可能细化表型并减少异质性。
The network theory of mental disorders conceptualizes psychiatric symptoms as networks of symptoms that causally interact with each other. Our present study aimed to explore the symptomatic structure in children with attention-deficit/hyperactivity disorder (ADHD) using network analyses. Symptom network based on 18 items of ADHD Rating Scale-IV was evaluated in 4,033 children and adolescents with ADHD. The importance of nodes was evaluated quantitatively by examining centrality indices, including Strength, Betweenness and Closeness, as well as Predictability and Expected Influence (EI). In addition, we compared the network structure across different subgroups, as characterized by ADHD subtypes, gender and age groups to evaluate its invariance. A three-factor-community structure was identified including inattentive, hyperactive and impulsive clusters. For the centrality indices, the nodes of “Distracted” and “Fidget” showed high closeness and betweenness, and represented a bridge linking the inattentive and hyperactive/impulsive domains. “Details” and “Fidget” were the most common endorsed symptoms in inattentive and hyperactive/impulsive domains respectively. On the contrary, the “Listen” item formed a peripheral node showing weak links with all other items within the inattentive cluster, and the “Loss” item as the least central node by all measures of centrality and with low predictability value. The network structure was relatively invariant across gender, age and ADHD subtypes/presentations. The 18 items of ADHD core symptoms appear not equivalent and interchangeable. “Distracted” and “Fidget” should be considered as central, or core, symptoms for further evaluation and intervention. The network-informed differentiation of these symptoms has the potentials to refine the phenotype and reduce heterogeneity.
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影响因子：
2.8
作者：
Heeren, Alexandre;McNally, Richard J.
通讯作者：
McNally, Richard J.
影响因子：
3.3
作者：
Karalunas SL;Antovich D;Goh PK;Martel MM;Tipsord J;Nousen EK;Nigg JT
通讯作者：
Nigg JT
DOI：
10.1146/annurev-clinpsy-050212-185608
发表时间：
2013-01-01
期刊：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 9
影响因子：
--
作者：
Borsboom, Denny;Cramer, Angelique O. J.
通讯作者：
Cramer, Angelique O. J.
DOI：
10.1016/j.psc.2009.12.004
发表时间：
2010-03
期刊：
The Psychiatric clinics of North America
影响因子：
--
作者：
Faraone SV;Mick E
通讯作者：
Mick E
揭示注意力缺陷/多动障碍的最佳潜在结构：支持 ICD 和 HiTOP 框架的证据
影响因子：
4.7
作者：
Gomez R;Liu L;Krueger R;Stavropoulos V;Downs J;Preece D;Houghton S;Chen W
通讯作者：
Chen W