Longitudinal network model of the co-development of temperament, executive functioning, and psychopathology symptoms in youth with and without ADHD.
Longitudinal network model of the co-development of temperament, executive functioning, and psychopathology symptoms in youth with and without ADHD.
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DOI：
10.1017/s0954579421000900
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发表时间：
2021-12
影响因子：
3.3
通讯作者：
Nigg JT
中科院分区：
文献类型：
--
作者：
Karalunas SL;Antovich D;Goh PK;Martel MM;Tipsord J;Nousen EK;Nigg JT
注意缺陷多动障碍（ADHD）是一种常见的慢性损害性疾病，但ADHD的表现和临床病程是高度异质性的。尽管进行了大量的研究工作，但（a）ADHD的继发性并发症和其他临床问题的复杂化以及（B）导致或远离青春期恢复的发育途径仍然知之甚少。解决这些问题需要考虑开发过程中大量特性的事务性影响。在这里，我们应用了一个纵向交叉滞后面板网络模型的多模态，多层次的数据集，在一个良好的表征样本的488名儿童（nADHD=296），以测试研究领域标准倡议启发的假设transdiagnosis风险。网络功能包括DSM症状，基于特质的情绪功能（气质）评级，和基于性能的认知措施。结果证实，ADHD症状领域，气质易怒，工作记忆是独立的transdiagnosis风险因素的精神病理学的基础上，他们的直接关联与其他功能跨时间。ADHD症状和工作记忆都与抑郁症有直接、独立的联系。结果还表明，ADHD症状和脾气暴躁的共同发展密切相关，这与这种类型的愤怒失调是一种核心特征的可能性相一致，这种核心特征作为某些儿童ADHD表型的一部分共同表达。
Attention Deficit Hyperactivity Disorder (ADHD) is a common, chronic, and impairing disorder, yet presentations of ADHD and clinical course are highly heterogeneous. Despite substantial research efforts, both (a) the secondary co-occurrence of ADHD and complicating additional clinical problems and (b) the developmental pathways leading toward or away from recovery through adolescence remain poorly understood. Resolving these requires accounting for transactional influences of a large number of features across development. Here, we applied a longitudinal cross-lagged panel network model to a multimodal, multilevel dataset in a well-characterized sample of 488 children (nADHD=296) to test Research Domain Criteria initiative-inspired hypotheses about transdiagnostic risk. Network features included DSM symptoms, trait-based ratings of emotional functioning (temperament), and performance-based measures of cognition. Results confirmed that ADHD symptom domains, temperamental Irritability, and Working Memory are independent transdiagnostic risk factors for psychopathology based on their direct associations with other features across time. ADHD symptoms and working memory each had direct, independent associations with depression. Results also demonstrated tightly linked co-development of ADHD symptoms and temperamental Irritability, consistent with the possibility that this type of anger dysregulation is a core feature that is co-expressed as part of the ADHD phenotype for some children.
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影响因子：
4.6
作者：
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DOI：
10.1146/annurev-clinpsy-071119-115831
发表时间：
2020-01-01
期刊：
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影响因子：
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作者：
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通讯作者：
Achenbach, Thomas M.
DOI：
10.1146/annurev-clinpsy-050212-185608
发表时间：
2013-01-01
期刊：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 9
影响因子：
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作者：
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通讯作者：
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DOI：
10.1016/j.jaac.2020.11.022
发表时间：
2021-12
影响因子：
13.3
作者：
Cardinale, Elise M.;Freitag, Gabrielle F.;Brotman, Melissa A.;Pine, Daniel S.;Leibenluft, Ellen;Kircanski, Katharina
通讯作者：
Kircanski, Katharina