Clindamycin-resistant group B Streptococcus and failure of intrapartum prophylaxis to prevent early-onset disease.

Clindamycin-resistant group B Streptococcus and failure of intrapartum prophylaxis to prevent early-onset disease.
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DOI:
10.1016/j.jpeds.2009.10.048
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发表时间:
2010-03
影响因子:
5.1
通讯作者:
Byington, Carrie L.
Byington, Carrie L.
中科院分区:
医学2区
文献类型:
--
作者:
Blaschke, Anne J.;Pulver, Laurie S.;Korgenski, E. Kent;Savitz, Lucy A.;Daly, Judy A.;Byington, Carrie L.

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指南建议对B组链球菌(GBS)筛查阳性的产妇进行产时抗生素预防(IAP)。只有当母体GBS分离株敏感时,才应将克林霉素用于IAP。我们报告一例克林霉素耐药GBS疾病的新生儿,其母亲接受克林霉素IAP,我们审查克林霉素药敏试验。
Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.
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