Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes

Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes
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乳糖基衍生物通过作为白细胞上整合素 CD11b 的拮抗剂在严重烧伤休克大鼠模型中发挥作用

DOI:
10.1007/s10719-008-9174-0
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发表时间:
2009-02
期刊:
Glycoconj J 2009; 26: 173–188 (*Corresponding author) (IF: 1.743)
影响因子:
--
通讯作者:
姜勇
姜勇
中科院分区:
其他
文献类型:
--
作者:
赵智辉;姜勇

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严重烧伤休克仍然是一个尚未解决的临床问题,迫切需要探索新的治疗方法。在这项研究中,对一系列合成的乳糖基衍生物(低聚糖)在烧伤休克大鼠体内的生物活性进行了评估。
Severe burn shock remains an unsolved clinical problem with urgent needs to explore novel therapeutic approaches. In this study, the in vivo bioactivity of a series of synthetic lactosyl derivatives (oligosaccharides) was assessed on rats with burn shock
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