The microbiome extends host evolutionary potential.

The microbiome extends host evolutionary potential.
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DOI:
10.1038/s41467-021-25315-x
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发表时间:
2021-08-26
影响因子:
16.6
通讯作者:
Ayroles JF
Ayroles JF
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Henry LP;Bruijning M;Forsberg SKG;Ayroles JF

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微生物组塑造了许多宿主的特征,然而微生物组的生物学挑战了传统的进化模型。在这里,我们说明了如何将微生物组整合到定量遗传学中可以帮助解开宿主-微生物组进化的复杂性。我们描述了微生物组可能影响宿主进化潜力的两种一般方式:通过改变宿主平均表型和通过改变种群中宿主表型的方差。我们综合了不同分类群的文献,并讨论了这些情景如何影响宿主对选择的反应。最后,我们概述了研究的关键途径,以提高我们对宿主和微生物群之间复杂相互作用的理解。微生物组被认为是宿主表型的关键决定因素。在这里,Henry等人提出了一个框架来构建我们对微生物组如何影响宿主进化的理解,回顾了经验例子和研究方法,并强调了新出现的问题。
The microbiome shapes many host traits, yet the biology of microbiomes challenges traditional evolutionary models. Here, we illustrate how integrating the microbiome into quantitative genetics can help untangle complexities of host-microbiome evolution. We describe two general ways in which the microbiome may affect host evolutionary potential: by shifting the mean host phenotype and by changing the variance in host phenotype in the population. We synthesize the literature across diverse taxa and discuss how these scenarios could shape the host response to selection. We conclude by outlining key avenues of research to improve our understanding of the complex interplay between hosts and microbiomes. The microbiome is becoming recognized as a key determinant of host phenotype. Here, Henry et al. present a framework for building our understanding of how the microbiome also influences host evolution, review empirical examples and research approaches, and highlight emerging questions.
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