Imaging techniques for prostate cancer: implications for focal therapy.

Imaging techniques for prostate cancer: implications for focal therapy.
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DOI:
10.1038/nrurol.2009.27
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发表时间:
2009-04
期刊:
Nature reviews. Urology
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前列腺癌的多灶性在过去需要全腺体治疗;然而,由于PSA筛查的广泛使用,患者经常出现不太晚期的疾病。许多患有局限性疾病的男性希望避免全腺体治疗的不良反应;因此,前列腺癌的局部治疗被认为是一种治疗选择。为了使病灶治疗可行,需要准确的成像来诊断、分期和监测治疗。MRI和PET的发展使人们更加关注前列腺成像和提高病灶治疗准确性的可能性。在这篇综述中,我们讨论了传统方法的优点和缺点,成像的前列腺,靶向成像的新发展,以及图像引导活检和治疗局部前列腺癌的可能作用。
The multifocal nature of prostate cancer has necessitated whole-gland therapy in the past; however, since the widespread use of PSA screening, patients frequently present with less-advanced disease. Many men with localized disease wish to avoid the adverse effects of whole-gland therapy; therefore, focal therapy for prostate cancer is being considered as a treatment option. For focal treatment to be viable, accurate imaging is required for diagnosis, staging, and monitoring of treatment. Developments in MRI and PET have brought more attention to prostate imaging and the possibility of improving the accuracy of focal therapy. In this Review, we discuss the advantages and disadvantages of conventional methods for imaging the prostate, new developments for targeted imaging, and the possible role of image-guided biopsy and therapy for localized prostate cancer.
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