Proportional bias of multifrequency bioimpedance analysis is larger in Hispanic females than males.

Proportional bias of multifrequency bioimpedance analysis is larger in Hispanic females than males.
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DOI:
10.1016/j.nutres.2022.03.007
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发表时间:
2022-07
期刊:
影响因子:
4.5
通讯作者:
Snarr, Ronald L.
Snarr, Ronald L.
中科院分区:
医学3区
文献类型:
--
作者:
Nickerson, Brett S.;Snarr, Ronald L.

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身体组成算法通常使用多种族人群进行验证,而不考虑种族。这可能是有问题的,当使用多频生物阻抗分析(MF-BIA)的西班牙裔。组错误(即,常数误差[CE]),个体误差(即,当使用双能X线吸收测定法(DXA)作为参考方法时,在西班牙裔男性和女性(分别为n = 84和97)中确定了MF-BIA的一致性[LOA]和比例偏倚。由于缺乏西班牙裔的种族特异性阻抗方程,因此假设MF-BIA与DXA相比存在偏倚。对于体脂百分比(BF%),与DXA相比,MF-BIA在样本(−3.17±5.45%)、男性(−3.2±5.5%)和女性(−3.2±5.4%)中显示出相似的CE±95% LOA。然而,女性存在中度比例偏倚(r=0.48)。样本(r=0.22)和男性(r=-0.04)存在轻微至无比例偏倚。关于脂肪量(FM),MF-BIA显示样本的CE±95% LOA值为−1.4±4.2 kg,男性为−1.9±4.6 kg,女性为−0.9±3.6 kg。女性存在强比例偏倚(=0.68),样本存在中度偏倚(r=0.36)。在男性中未观察到比例偏倚(r=-0.02)。对于去脂质量(FFM),当将MF-BIA与DXA进行比较时,与样本(1.2±3.9 kg)和雌性(0.9±3.4 kg)相比,雄性显示出最大CE±95% LOA(1.6±4.6)。样本(r=-0.01)或男性(r=-0.10)不存在比例偏倚。然而,女性表现出中度负偏倚(r=-0.38)。由于观察到的中度到强烈的比例偏差内的身体成分估计,种族特定的算法的需要是必要的,特别是对西班牙裔女性人口。DXA =双能X线吸收测定法; MF-BIA =多频生物阻抗分析; FFM =去脂质量; BF% =体脂百分比; CE =恒定误差;散点图上的中间实线表示CE。虚线表示一致性的上限和下限(± 1.96 SD)。点划线回归线表示比例偏倚。
Body composition algorithms are typically validated using multi-ethnic populations without accounting for ethnicity. This might be problematic when using multi-frequency bioimpedance analysis (MF-BIA) for Hispanics. Group error (i.e., constant error [CE]), individual error (i.e., 95% limits of agreement [LOAs]), and proportional bias of MF-BIA were determined in Hispanic men and women (n = 84 and 97, respectively) when using dual energy X-ray absorptiometry (DXA) as a reference method. Due to the lack of an ethnic-specific impedance equation for Hispanics, it was hypothesized that MF-BIA would be biased when compared to DXA. For body fat percent (BF%), MF-BIA displayed similar CE±95% LOA for the sample (−3.17±5.45%), males (−3.2±5.5%), and females (−3.2±5.4%) compared to DXA. However, moderate proportional bias was present for females (r=0.48). The sample (r=0.22) and males (r=−0.04) had trivial-to-no proportional bias. Regarding fat mass (FM), MF-BIA exhibited CE±95% LOA values of −1.4±4.2 kg for the sample, −1.9±4.6 kg for males, and −0.9±3.6 kg for females. There was strong proportional bias for females (=0.68) and moderate bias for the sample (r=0.36). No proportional bias was observed for males (r=−0.02). For fat-free mass (FFM), males demonstrated the largest CE±95% LOA (1.6±4.6), compared to the sample (1.2±3.9 kg) and females (0.9±3.4 kg) when MF-BIA was compared to DXA. No proportional biases existed for the sample (r=−0.01) or males (r=−0.10). However, females exhibited a moderate, negative bias (r=−0.38). Due to the observed moderate-to-strong proportional biases within body composition estimates, the need for ethnic-specific algorithms is warranted, particularly for the Hispanic female population. DXA = Dual-energy x-ray absorptiometry; MF-BIA = Multi-frequency bioimpedance analysis; FFM = Fat-free mass; BF% = Body fat percentage; CE = Constant Error; The middle solid lines on the scatterplots indicate CE. The dashed lines represent the upper and lower limits of agreement (± 1.96 SD). The dashed-dotted regression lines represent the proportional bias.
DOI: 10.3390/jfmk4020023
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