Regulation of ribosomal RNA transcription during differentiation of Acanthamoeba castellanii: a review.

Regulation of ribosomal RNA transcription during differentiation of Acanthamoeba castellanii: a review.
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卡氏棘阿米巴分化过程中核糖体 RNA 转录的调控:综述。

DOI:
10.1111/j.1550-7408.1983.tb02905.x
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发表时间:
1983
期刊:
The Journal of protozoology
影响因子:
--
通讯作者:
Paule,MR
Paule,MR
中科院分区:
--
文献类型:
--
作者:
Paule,MR

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在饥饿诱导卡氏阿米巴细胞分化过程中,许多基因的表达受到调控。有证据表明,至少其中之一,前体核糖体RNA转录单位,在转录水平进行调节。本文综述了在阿米巴原虫中rRNA转录单位和负责转录的RNA聚合酶的结构。利用由这些组分构建的体外转录系统,已经获得了初步证据,即前rRNA基因表达受RNA聚合酶I的修饰调节,该修饰影响酶有效参与转录起始的能力。这些结果进行审查有关其他已知的机制,在真核生物中的转录调控。
During the cellular differentiation induced by starvation ofAcanthamoeba castellanii, the expression of a number of genes is regulated. Evidence is reviewed that at least one of these, the precursor ribosomal RNA transcription unit, is regulated at the level of transcription. The structure of the rRNA transcription unit and of the RNA polymerases responsible for transcription inAcanthamoebaare reviewed. Utilizing an in vitro transcription system constructed from these components, preliminary evidence has been obtained that pre‐rRNA gene expression is regulated by a modification of RNA polymerase I that affects the enzyme's ability to participate efficiently in the initiation of transcription. These results are reviewed in relation to other known mechanisms of transcriptional regulation in eukaryotes.
DOI: 10.1016/0092-8674(80)90160-9
发表时间: 1980-01-01
期刊: CELL
影响因子: 64.5
作者:
HONDA, BM;ROEDER, RG
通讯作者: ROEDER, RG
棘阿米巴的生长、繁殖和分化。
DOI: --
发表时间: 1979
期刊: International Review of Cytology
影响因子: --
作者:
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DOI: --
发表时间: 1979
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作者:
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通讯作者: I. Grummt
DOI: --
发表时间: 1979
影响因子: 4.8
作者:
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