Incidence and prevalence of juvenile idiopathic arthritis among children in a managed care population, 1996-2009.
Incidence and prevalence of juvenile idiopathic arthritis among children in a managed care population, 1996-2009.
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DOI：
10.3899/jrheum.120661
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发表时间：
2013-07
期刊：
影响因子：
--
通讯作者：
Herrinton LJ
中科院分区：
文献类型：
--
作者：
Harrold LR;Salman C;Shoor S;Curtis JR;Asgari MM;Gelfand JM;Wu JJ;Herrinton LJ
很少有基于明确定义的北美人群的研究检查了幼年特发性关节炎（JIA）的发生，没有一项研究是基于种族多样性的人群。我们使用来自Kaiser Permanente北方加州会员的计算机化医疗保健信息来验证JIA诊断并估计该疾病在这一特征良好的人群中的发病率和患病率。我们在1996-2009年期间的计算机化临床就诊数据中，确定了年龄≤ 15岁且相关国际疾病分类（第9版）诊断代码为696.0、714或720的儿童。在随机样本中，我们然后审查了医疗记录，以确认诊断和诊断日期，并确定最佳的病例发现算法。最后，我们使用病例发现算法来估计JIA的发病率和点患病率。在至少有1个相关编码的个体中，69%的人确诊为JIA。45%是在研究期间新诊断的。年龄和性别标准化的JIA发病率为11.9/10万人年（95%CI 10.9-12.9）。女孩为16.4（95% CI 14.6-18.1），男孩为7.7（95% CI 6.5-8.9）。发病高峰出现在11-15岁儿童。2009年12月31日，每10万人中JIA的患病率为44.7（95%CI 39.1-50.2）。1996-2009年，在Kaiser Permanente人群中观察到的JIA发病率与美国明尼苏达州罗切斯特报告的发病率相似，但比加拿大估计值高2 - 3倍。
Few studies based in well-defined North American populations have examined the occurrence of juvenile idiopathic arthritis (JIA), and none has been based in an ethnically diverse population. We used computerized healthcare information from the Kaiser Permanente Northern California membership to validate JIA diagnoses and estimate the incidence and prevalence of the disease in this well-characterized population. We identified children aged ≤ 15 years with ≥ 1 relevant International Classification of Diseases, 9th edition, diagnosis code of 696.0, 714, or 720 in computerized clinical encounter data during 1996–2009. In a random sample, we then reviewed the medical records to confirm the diagnosis and diagnosis date and to identify the best-performing case-finding algorithms. Finally, we used the case-finding algorithms to estimate the incidence rate and point prevalence of JIA. A diagnosis of JIA was confirmed in 69% of individuals with at least 1 relevant code. Forty-five percent were newly diagnosed during the study period. The age- and sex-standardized incidence rate of JIA per 100,000 person-years was 11.9 (95% CI 10.9–12.9). It was 16.4 (95% CI 14.6–18.1) in girls and 7.7 (95% CI 6.5–8.9) in boys. The peak incidence rate occurred in children aged 11–15 years. The prevalence of JIA per 100,000 persons was 44.7 (95% CI 39.1–50.2) on December 31, 2009. The incidence rate of JIA observed in the Kaiser Permanente population, 1996–2009, was similar to that reported in Rochester, Minnesota, USA, but 2 to 3 times higher than Canadian estimates.
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影响因子：
27.4
作者：
von Koskull, S;Truckenbrodt, H;Hörmann, A
通讯作者：
Hörmann, A
影响因子：
--
作者：
Nordal, Ellen;Zak, Marek;Rygg, Marite
通讯作者：
Rygg, Marite
DOI：
10.1016/j.berh.2010.05.007
发表时间：
2010-10-01
影响因子：
5.2
作者：
Rudwaleit, Martin;Taylor, William J.
通讯作者：
Taylor, William J.
影响因子：
7.2
作者：
Couris, Chantal Marie;Polazzi, Stephanie;Trombert, Beatrice
通讯作者：
Trombert, Beatrice
影响因子：
4.7
作者：
Beukelman, Timothy;Patkar, Nivedita M.;Saag, Kenneth G.;Tolleson-Rinehart, Sue;Cron, Randy Q.;DeWitt, Esi Morgan;Ilowite, Norman T.;Kimura, Yukiko;Laxer, Ronald M.;Lovell, Daniel J.;Martini, Alberto;Rabinovich, C. Egla;Ruperto, Nicolino
通讯作者：
Ruperto, Nicolino