Long‐term hazards of neonatal blue‐light phototherapy
Long‐term hazards of neonatal blue‐light phototherapy
复制标题
新生儿蓝光光疗的长期危害
DOI：
10.1111/bjd.12335
复制
发表时间：
2013
影响因子：
10.3
通讯作者：
Z. Csoma
中科院分区：
文献类型：
--
作者：
J. Oláh;E. Tóth;Lajos Kemény;Lajos Kemény;Z. Csoma
几十年来，蓝光光疗一直是新生儿黄疸管理的重要治疗工具。它很少伴有急性皮肤和全身副作用，但幸运的是，这些副作用是可逆的，可以在常规新生儿实践中得到充分和及时的治疗。相比之下，对新生儿蓝光光疗（NBLP）的潜在长期副作用知之甚少。目前关于NBLP如何影响黑素细胞痣（MN）发展的许多数据存在争议。最近精心设计的流行病学调查结果表明，NBLP很可能是MN形成的风险因素，并强调需要进行额外的体内和体外研究。NBLP目前是新生儿黄疸治疗的主要方法，但未来在需要光疗时应更多地考虑其长期副作用。有必要强调适当限制和充分的临床指南的重要性，以及对高胆红素血症管理的严格监测，以避免对新生儿不必要的过度治疗。
Blue‐light phototherapy has been an essential therapeutic tool in the management of neonatal jaundice for decades. Rarely, it is accompanied by acute dermatological and systemic side‐effects, but fortunately these are reversible and can be adequately and promptly treated in routine neonatal practice. In contrast, much less is known about the potential long‐term side‐effects of neonatal blue‐light phototherapy (NBLP). Many of the data that are currently available on how NBLP influences melanocytic naevus (MN) development are controversial. The results of recent well‐designed epidemiological surveys suggest that NBLP could well be a risk factor for MN formation, and highlight the need for additional in vivo and in vitro studies. NBLP is at present the mainstay of treatment for neonatal jaundice, but in the future greater consideration should be given to its long‐term side‐effects when phototherapy is indicated. It is relevant to emphasize the importance of appropriately restricted and adequate clinical guidelines, and strict monitoring of the management of hyperbilirubinaemia, in order to avoid the unnecessary overtreatment of newborn infants.
DOI：
10.1056/nejmoa0803024
发表时间：
2008-10-30
期刊：
The New England journal of medicine
影响因子：
--
作者：
Morris BH;Oh W;Tyson JE;Stevenson DK;Phelps DL;O'Shea TM;McDavid GE;Perritt RL;Van Meurs KP;Vohr BR;Grisby C;Yao Q;Pedroza C;Das A;Poole WK;Carlo WA;Duara S;Laptook AR;Salhab WA;Shankaran S;Poindexter BB;Fanaroff AA;Walsh MC;Rasmussen MR;Stoll BJ;Cotten CM;Donovan EF;Ehrenkranz RA;Guillet R;Higgins RD;NICHD Neonatal Research Network
通讯作者：
NICHD Neonatal Research Network
黑色素瘤患者和比较对象中临床非典型（发育不良）痣的人口统计学研究。
影响因子：
11.2
作者：
Nordlund,JJ;Kirkwood,J;Forget,BM;Scheibner,A;Albert,DM;Lerner,E;Milton,GW
通讯作者：
Milton,GW
DOI：
10.1146/annurev-pathol-012513-104658
发表时间：
2014
期刊：
Annual review of pathology
影响因子：
--
作者：
Bastian BC
通讯作者：
Bastian BC