Cost Analysis of Treating Neonatal Hypoglycemia with Dextrose Gel.
Cost Analysis of Treating Neonatal Hypoglycemia with Dextrose Gel.
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DOI：
10.1016/j.jpeds.2018.02.036
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Children with Hypoglycemia and Their Later Development (CHYLD) Study Team
中科院分区：
文献类型：
--
作者：
Glasgow MJ;Harding JE;Edlin R;Children with Hypoglycemia and Their Later Development (CHYLD) Study Team
评价在出生后48小时内使用葡萄糖凝胶作为新生儿低血糖症的主要治疗方法与标准治疗方法的成本。我们使用决策树来模拟总体成本，包括低血糖监测和治疗的具体成本以及与婴儿在产后病房或新生儿重症监护室的住院时间相关的成本，使用来自Sugar Babies随机试验的数据，比较使用葡萄糖凝胶治疗新生儿低血糖与安慰剂。敏感性分析评估了葡萄糖凝胶成本、新生儿重症监护成本、剖宫产率和血糖监测成本的影响。在初步分析中，使用葡萄糖凝胶治疗新生儿低血糖的总成本为6，863.81新西兰元，标准护理（安慰剂）成本为8，178.25新西兰元;每名接受治疗的婴儿节省1，314.44新西兰元。敏感性分析表明，葡萄糖凝胶仍然节省成本，葡萄糖凝胶成本，新生儿重症监护室成本，剖宫产率和监测成本的变化很大。口腔葡萄糖凝胶的使用降低了新生儿低血糖症的住院费用。由于它也是非侵入性的，耐受性好，安全，并与改善母乳喂养，口腔葡萄糖凝胶应常规用于新生儿低血糖症的初始治疗。
To evaluate the costs of using dextrose gel as a primary treatment for neonatal hypoglycemia in the first 48 hours after birth compared with standard care. We used a decision tree to model overall costs, including those specific to hypoglycemia monitoring and treatment and those related to the infant’s length of stay on the postnatal ward or neonatal intensive care unit, comparing the use of dextrose gel for treatment of neonatal hypoglycemia with placebo, using data from the Sugar Babies randomized trial. Sensitivity analyses assessed the impact of dextrose gel cost, neonatal intensive care cost, cesarean delivery rate and costs of glucose monitoring. In the primary analysis, treating neonatal hypoglycemia using dextrose gel had an overall cost of NZ$6,863.81 and standard care (placebo) cost NZ$8,178.25; a saving of NZ$1,314.44 per infant treated. Sensitivity analyses showed that dextrose gel remained cost saving with wide variations in dextrose gel costs, neonatal intensive care unit costs, cesarean delivery rates and costs of monitoring. Use of buccal dextrose gel reduces hospital costs for management of neonatal hypoglycemia. Because it is also non-invasive, well tolerated, safe and associated with improved breast-feeding, buccal dextrose gel should be routinely utilized for initial treatment of neonatal hypoglycemia.
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影响因子：
5.2
作者：
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