The application of SELDI-TOF-MS in clinical diagnosis of cancers.

The application of SELDI-TOF-MS in clinical diagnosis of cancers.
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DOI:
10.1155/2011/245821
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发表时间:
2011
影响因子:
--
通讯作者:
Liu C
Liu C
中科院分区:
其他
文献类型:
--
作者:
Liu C

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癌症诊断很重要,癌症的早期诊断可以预测更成功的治疗。蛋白质组学研究在患者样本的联合分析中变得有用,并且与基于单因素的诊断相比,提供了更准确的诊断。近年来,表面增强激光解吸电离飞行时间质谱(SELDI-TOF MS)技术在癌症检测中的应用蓬勃发展,并取得了重大进展。本文总结了一些最近的结果与该技术的癌症诊断。
Cancer diagnosis is important, and the early diagnosis of cancers could predict a more successful treatment. The proteomic studies emerged to be useful in combined analyses of samples from patients and provide more accurate diagnosis when compared to the single-factor-based diagnosis. In recent years, cancer detection with surface-enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF MS) is flourishing and brought significant progress in this area. This paper summarizes some recent results with this technique for cancer diagnosis.
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