New developments in microbial interspecies signaling.

New developments in microbial interspecies signaling.
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DOI:
10.1016/j.mib.2009.01.003
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发表时间:
2009-04
影响因子:
5.4
通讯作者:
Kolter, Roberto
Kolter, Roberto
中科院分区:
生物学2区
文献类型:
--
作者:
Shank, Elizabeth Anne;Kolter, Roberto

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越来越多的人认识到,除了有据可查的种内群体感应系统之外,小分子还充当不同物种微生物之间的信号。本文将重点介绍细菌小分子如何调节这些种间相互作用。我们将特别强调复杂的关系,如微生物和昆虫之间的关系,导致非拮抗结果(即发育和形态学过程)的相互作用,共培养如何导致发现新的小分子,以及使用已知化合物来引起意想不到的反应和介导微生物之间的串扰。
There is a growing appreciation that in addition to well-documented intraspecies quorum sensing systems, small molecules act as signals between microbes of different species. This review will focus on how bacterial small molecules modulate these interspecies interactions. We will particularly emphasize complex relationships such as those between microbes and insects, interactions resulting in non-antagonistic outcomes (i.e. developmental and morphological processes), how co-culture can lead to the discovery of new small molecules, and the use of known compounds to evoke unexpected responses and mediate crosstalk between microbes.
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