Molecular Recognition of Carbohydrates: Evaluation of the Binding Properties of Pyrazole-based receptors and their Comparison with Imidazole- and Indole-based Systems

Molecular Recognition of Carbohydrates: Evaluation of the Binding Properties of Pyrazole-based receptors and their Comparison with Imidazole- and Indole-based Systems
复制标题

碳水化合物的分子识别:吡唑基受体的结合特性评估及其与咪唑和吲哚基系统的比较

DOI:
10.1177/1934578x1200700311
复制
发表时间:
2012
影响因子:
1.8
通讯作者:
M. Mazik
M. Mazik
中科院分区:
医学4区
文献类型:
--
作者:
Claudia Sonnenberg;A. Hartmann;M. Mazik

文献摘要

参考文献

被引文献

相似文献

这项研究的目的是评估基于吡唑的受体在碳水化合物络合中的潜力。合成了一系列新型无环吡唑受体的代表化合物,并评价了它们与选定的单糖和双糖的结合性能。结合研究的结果与基于无环咪唑和吲哚的受体的结合研究结果进行了比较。第一次结合研究揭示了新受体的不同单糖结合偏好,并表明吡唑单元是构建具有有趣结合偏好的受体的有用构件。
The aim of the study was to evaluate the potential of pyrazole-based receptors in the complexation of carbohydrates. Representatives of a new series of acyclic pyrazole-based receptors were prepared and their binding properties toward selected mono- and disaccharides evaluated. The results of the binding studies were compared with those obtained for acyclic imidazole- and indole-based receptors. The first binding studies revealed di- vs monosaccharide binding preferences of the new receptors and showed that pyrazole units are useful building blocks for the construction of receptors with interesting binding preferences.
8-羟基喹啉作为人工受体的构建模块:吡喃糖苷识别中的结合偏好
DOI: 10.1039/c0ob00960a
发表时间: 2011
影响因子: 3.2
作者:
M. Mazik;C. Geffert
通讯作者: C. Geffert
基于菲咯啉的受体对碳水化合物的高效识别:α-与β-端基异构体结合偏好
DOI: 10.1002/chem.200900664
发表时间: 2009
期刊: Chemistry
影响因子: --
作者:
M. Mazik;A. Hartmann;P. G. Jones
通讯作者: P. G. Jones