Childhood and adolescent psychiatric disorders as predictors of young adult disorders.
Childhood and adolescent psychiatric disorders as predictors of young adult disorders.
复制标题
DOI：
10.1001/archgenpsychiatry.2009.85
复制
发表时间：
2009-07
影响因子：
--
通讯作者：
Angold, Adrian
中科院分区：
文献类型：
--
作者：
Copeland, William E.;Shanahan, Lilly;Costello, E. Jane;Angold, Adrian
大多数患有精神疾病的成年人在儿童和/或青春期首次达到诊断标准，但具体的同型和异型预测模式尚未确定。确定儿童和青少年精神疾病预测特定的年轻成人疾病时，占合并症，分解类似的疾病，并分别检查儿童和青少年的预测因子。研究使用了来自大烟山前瞻性人群研究（N = 1,420）的11波数据，涵盖了社区中9 - 16岁、19岁和21岁的儿童。儿童期（9至12岁）和青少年期（13至16岁）的常见精神疾病采用儿童和青少年精神病评估进行评估，青年期（19至21岁）采用青年精神病评估进行评估。在双变量分析中，青少年抑郁症显著预测年轻成人抑郁症，但在校正分析中，这种效应完全由青少年抑郁症与青少年对立违抗性障碍、焦虑和物质障碍的共病引起。广泛性焦虑和抑郁相互交叉预测，对立违抗性障碍（但不是行为障碍）预测后来的焦虑症和抑郁症。物质使用障碍、反社会人格障碍（来自品行障碍）和焦虑障碍支持同型预测的证据，尽管这种影响主要由DSM-III-R过度焦虑障碍解释。同型和异型预测模式的严格测试表明，与以前的文献相比，在发育和诊断上有更细微的差别。青少年抑郁症和青年抑郁症之间的假定联系没有得到支持。对立违抗性障碍是一个独特的发展历史的一部分，广泛的年轻成人的障碍。
Most adults with a psychiatric disorder first met diagnostic criteria during childhood and/or adolescence, yet specific homotypic and heterotypic patterns of prediction have not been firmly established. To establish which childhood and adolescent psychiatric disorders predict particular young adult disorders when accounting for comorbidities, disaggregating similar disorders, and examining childhood and adolescent predictors separately. Eleven waves of data from the prospective population-based Great Smoky Mountains Study (N = 1,420) were used, covering children in the community ages 9−16, 19, and 21 years old. Common psychiatric disorders were assessed in childhood (ages 9 to 12) and adolescence (ages 13 to 16) with the Child and Adolescent Psychiatric Assessment, and in young adulthood (ages 19 and 21) with the Young Adult Psychiatric Assessment. Adolescent depression significantly predicted young adult depression in the bivariate analysis, but this effect was entirely accounted for by comorbidity of adolescent depression with adolescent oppositional defiant disorder, anxiety and substance disorders in adjusted analyses. Generalized anxiety and depression cross-predicted each other, and oppositional defiant disorder (but not conduct disorder) predicted later anxiety disorders and depression. Evidence of homotypic prediction was supported for substance use disorders, antisocial personality disorder (from conduct disorder) and anxiety disorders, although this effect was primary accounted for by DSM-III-R overanxious disorder. Stringent tests of homotypic and heterotypic prediction patterns suggest a more developmentally and diagnostically nuanced picture in comparison with the previous literature. The putative link between adolescent and young adult depression was not supported. Oppositional defiant disorder was singular in being part of the developmental history of a wide range of young adult disorders.
登录
查看更多内容
影响因子：
--
作者：
Jaffee, SR;Moffitt, TE;Martin, J
通讯作者：
Martin, J
DOI：
10.1097/00004583-200202000-00012
发表时间：
2002-02-01
影响因子：
13.3
作者：
Hofstra, MB;van der Ende, J;Verhulst, FC
通讯作者：
Verhulst, FC
DOI：
10.1016/j.chc.2005.06.003
发表时间：
2005-10-01
影响因子：
2.4
作者：
Costello, EJ;Egger, HL;Angold, A
通讯作者：
Angold, A
影响因子：
7.6
作者：
Angold, A;Erkanli, A;Costello, EJ
通讯作者：
Costello, EJ
影响因子：
11.3
作者：
BRESLAU, N;SCHULTZ, L;PETERSON, E
通讯作者：
PETERSON, E