Personality and EQ-5D scores among individuals with chronic conditions.

Personality and EQ-5D scores among individuals with chronic conditions.
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DOI:
10.1007/s11136-008-9401-y
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发表时间:
2008-11
影响因子:
3.5
通讯作者:
Franks, Peter
Franks, Peter
中科院分区:
医学2区
文献类型:
--
作者:
Jerant, Anthony;Chapman, Benjamin P.;Franks, Peter

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个性与自我评估的健康有关,但之前的研究没有检查过与基于偏好的衡量标准的相关性。我们假设,基于偏好的健康也会存在类似的关联。我们分析了参加自我管理干预的慢性病患者的基线数据。以EQ-5D综合指数得分和维度得分(活动能力、自我照顾、日常活动、疼痛/不适、焦虑/抑郁)为因变量进行回归分析,关键自变量为新五因素问卷(NEO-FFI)人格因素(神经质、严谨性、外向性、开放性、宜人性),调整了年龄、性别、文化程度、少数民族状况和慢性病。在415名参与者中,245名(59%)患有≥2慢性病,384名(94%)完成了NEO-FFI,397名(96%)完成了EQ-5D。调整后,神经质与EQ-5D总分相关[神经质每增加1个SD,−为0.04(95%CI−0.06,−0.01)]。神经质[AOR2.99(95%CI 2.06,4.35;P<0.001)]和开放性[1.32(95%CI 1.00,1.75;P=0.05)]与较差的焦虑/抑郁评分相关,而尽责与较好的日常活动评分[0.66(95%CI 0.49,0.89;P=0.01)]相关。人格因素和自我评估健康之间的关联似乎延伸到了基于偏好的衡量标准。未来的研究应该探索在成本效益分析中,个性是否会影响基于偏好的健康估计。
Personality is associated with self-rated health, but prior studies have not examined associations with preference-based measures. We hypothesized similar associations would exist with preference-based health. We analyzed baseline data from chronically ill individuals enrolled in a self-management intervention. We conducted regression analyses with the EQ-5D summary index score and dimension scores (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) as dependent variables, The key independent variables were NEO-Five Factor Inventory (NEO-FFI) personality factors (Neuroticism, Conscientiousness, Extraversion, Openness, Agreeableness), adjusting for age, gender, educational level, minority status, and chronic conditions. Of 415 participants, 245 (59%) had ≥2 chronic conditions, 384 (94%) completed the NEO-FFI and 397 (96%) the EQ-5D. After adjustment, Neuroticism was associated with EQ-5D summary index scores [−0.04 per 1 SD increase in Neuroticism (95% CI −0.06, −0.01)]. Neuroticism [AOR 2.99 (95% CI 2.06, 4.35; P < 0.001)] and Openness [1.32 (95% CI 1.00, 1.75; P = 0.05)] were associated with worse anxiety/depression scores, while Conscientiousness was associated with better usual activities scores [0.66 (95% CI 0.49, 0.89; P = 0.01)]. The associations between personality factors and self-rated health appear to extend to preference-based measures. Future studies should explore whether personality affects preference-based health estimates in cost-effectiveness analyses.
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