Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review.
Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review.
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DOI：
10.2147/cmar.s153482
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发表时间：
2018
影响因子：
3.3
通讯作者：
Yang X
中科院分区：
文献类型：
--
作者：
Han S;Gao J;Zhou Q;Liu S;Wen C;Yang X
结直肠癌是人类最常见的恶性肿瘤之一。最近的研究表明，结直肠癌是一种细菌失调引起的疾病；然而，肠道细菌在结直肠癌中的作用尚不清楚。本文就肠道菌群在结直肠癌中的作用作一综述。经鉴定筛选，共纳入57篇文献。从碳水化合物代谢、脂质代谢和氨基酸代谢三个代谢角度分析结直肠癌花代谢产物的相关文献。通过对既往文献的分析，从代谢角度构建肠道菌群作用的关联网络，为结肠直肠癌肠道菌群的进一步研究提供方向和思路。
Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives – including carbohydrate, lipid, and amino acid metabolism – was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer.
结直肠癌病因中的粪便胆酸和梭状芽胞杆菌。
影响因子：
8.8
作者：
Murray, W R;Backwood, A;Trotter, J M;Calman, K C;MacKay, C
通讯作者：
MacKay, C